Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease
(COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression …

Background Recent studies suggest that lung microbiome dysbiosis, the disease associated
disruption of the lung microbial community, might play a key role in chronic obstructive …

Chronic Obstructive Pulmonary Disease (COPD) has significantly contributed to global
mortality, with three million deaths reported annually. This impact is expected to increase …

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder with a
course that is not uniform for all COPD patients. Although smoking is considered as the …

Chronic obstructive pulmonary disease (COPD) is heterogeneous in development,
progression, and phenotypes. Little is known about the lung microbiome, sampled by …

Background Alterations in the composition of the lung microbiome associated with adverse
clinical outcomes, known as dysbiosis, have been implicated with disease severity and …

COPD, asthma, and cystic fibrosis (CF) are obstructive lung diseases with distinct
pathophysiologies and clinical phenotypes. In this paper, we highlight recent advances in …

The exact pathogenesis of chronic obstructive pulmonary disease (COPD) remains largely
unknown. While current management strategies are effective at stabilizing the disease or …

The mechanistic role of the airway microbiome in chronic obstructive pulmonary disease
(COPD) remains largely unexplored. We present a landscape of airway microbe–host …

Increasing evidence suggests that the lung microbiome plays an important role in chronic
obstructive pulmonary disease (COPD) severity. However, the dynamics of the lung …