Kaempferol and fisetin-related signaling pathways induce apoptosis in head and neck cancer cells
Despite the relative effectiveness of standard cancer treatment strategies, head and neck
cancer (HNC) is still considered one of the leading causes of mortality and morbidity. While …
cancer (HNC) is still considered one of the leading causes of mortality and morbidity. While …
Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells
HS Lee, HJ Cho, R Yu, KW Lee, HS Chun… - International journal of …, 2014 - mdpi.com
We previously noted that kaempferol, a flavonol present in vegetables and fruits, reduced
cell cycle progression of HT-29 cells. To examine whether kaempferol induces apoptosis of …
cell cycle progression of HT-29 cells. To examine whether kaempferol induces apoptosis of …
Anticancer potential of selected flavonols: Fisetin, kaempferol, and quercetin on head and neck cancers
Flavonols are ones of the most common phytochemicals found in diets rich in fruit and
vegetables. Research suggests that molecular functions of flavonoids may bring a number of …
vegetables. Research suggests that molecular functions of flavonoids may bring a number of …
Kaempferol increases apoptosis in human cervical cancer HeLa cells via PI3K/AKT and telomerase pathways
E Kashafi, M Moradzadeh, A Mohamadkhani… - Biomedicine & …, 2017 - Elsevier
Cervical cancer is one of the most frequent cancers in women worldwide. Defects in the
apoptotic pathways are responsible for both the disease pathogenesis and its therapy …
apoptotic pathways are responsible for both the disease pathogenesis and its therapy …
Kaempferol regresses carcinogenesis through a molecular cross talk involved in proliferation, apoptosis and inflammation on human cervical cancer cells, HeLa
Kaempferol, a flavonoid, contains a plethora of therapeutic properties and has demonstrated
its efficacy against cancer. This study aims to unravel the molecular targets that are being …
its efficacy against cancer. This study aims to unravel the molecular targets that are being …
Fisetin inhibits laryngeal carcinoma through regulation of AKT/NF-κB/mTOR and ERK1/2 signaling pathways
XJ Zhang, SS Jia - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Targeting cancer cells is crucial for improving the efficiency of laryngeal cancer treatment.
However, the signaling pathway and therapeutic strategy, related to the tumor, still need …
However, the signaling pathway and therapeutic strategy, related to the tumor, still need …
Kaempferol induces apoptosis in human lung non-small carcinoma cells accompanied by an induction of antioxidant enzymes
HWC Leung, CJ Lin, MJ Hour, WH Yang… - Food and Chemical …, 2007 - Elsevier
Kaempferol (3, 4′, 5, 7-tetrahydroxyflavone) is one of the most commonly found dietary
flavonols. The biological and pharmacological effects of kaempferol may depend upon its …
flavonols. The biological and pharmacological effects of kaempferol may depend upon its …
Kaempferol induces apoptosis in human HCT116 colon cancer cells via the Ataxia-Telangiectasia Mutated-p53 pathway with the involvement of p53 Upregulated …
W Li, B Du, T Wang, S Wang, J Zhang - Chemico-Biological Interactions, 2009 - Elsevier
Dietary flavonols have been found to possess preventive and therapeutic potential against
several kinds of cancers. This study is conducted to investigate the anti-proliferation effects …
several kinds of cancers. This study is conducted to investigate the anti-proliferation effects …
Anti-cancer effect and underlying mechanism (s) of kaempferol, a phytoestrogen, on the regulation of apoptosis in diverse cancer cell models
SH Kim, KC Choi - Toxicological research, 2013 - Springer
Phytoestrogens exist in edible compounds commonly found in fruits or plants. For long
times, phytoestrogens have been used for therapeutic treatments against human diseases …
times, phytoestrogens have been used for therapeutic treatments against human diseases …
The natural flavones, acacetin and apigenin, induce Cdk-Cyclin mediated G2/M phase arrest and trigger ROS-mediated apoptosis in glioblastoma cells
Brain and CNS-related cancers are rare; however, 0.3 million incidences and 0.24 million
deaths in 2018 demonstrates the unrelenting associated dangers. Glioblastoma is a brain …
deaths in 2018 demonstrates the unrelenting associated dangers. Glioblastoma is a brain …