Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development

BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …

Neurodegenerative pathways in Alzheimer's disease: a review

AK Ramachandran, S Das, A Joseph… - Current …, 2021 - ingentaconnect.com
Alzheimer's disease (AD) is a complex neurodegenerative disease that leads to insidious
deterioration of brain functions and is considered the sixth leading cause of death in the …

Recent update on the Alzheimer's disease progression, diagnosis and treatment approaches

A Malaiya, M Singhai, M Singh, SK Prajapati… - Current Drug …, 2022 - ingentaconnect.com
Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative disorder,
manifested by the loss of memory and cognitive abilities, behavioral disturbance and …

The neurobiology and pharmacotherapy of Alzheimer's disease

O Felician, TA Sandson - The Journal of neuropsychiatry …, 1999 - Am Neuropsych Assoc
Alzheimer's disease (AD), the most common cause of dementia, has become a major public
health concern as our population ages. In recent years, AD has attracted the attention of a …

Concepts for the treatment of Alzheimer's disease: molecular mechanisms and clinical application

C Pietrzik, C Behl - International journal of experimental …, 2005 - Wiley Online Library
To date, various strategies have been developed in order to prevent or to slow down the
progression of Alzheimer's disease (AD). Despite the medical need for an effective …

Insights into the pathophysiology of Alzheimer's disease and potential therapeutic targets: A current perspective

K Rajah Kumaran, S Yunusa, E Perimal… - Journal of …, 2023 - content.iospress.com
The aging population increases steadily because of a healthy lifestyle and medical
advancements in healthcare. However, Alzheimer's disease (AD) is becoming more …

Alzheimer's disease; a review of the pathophysiological basis and therapeutic interventions

A Abeysinghe, R Deshapriya, C Udawatte - Life sciences, 2020 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder and is identified as the most
common cause for dementia. Despite huge global economic burden and the impact on the …

Multifaceted Alzheimer's disease: Building a roadmap for advancement of novel therapies

D Kaur, T Behl, A Sehgal, S Singh, N Sharma… - Neurochemical …, 2021 - Springer
Alzheimer's disease (AD) is one of the most prevailing neurodegenerative disorders of
elderly humans associated with cognitive damage. Biochemical, epigenetic, and …

Alzheimer's disease: the challenge of the second century

DM Holtzman, JC Morris, AM Goate - Science translational medicine, 2011 - science.org
Alzheimer's disease (AD) was first described a little more than 100 years ago. It is the most
common cause of dementia with an estimated prevalence of 30 million people worldwide, a …

Alzheimer's disease: pathological mechanisms and recent insights

DM Niedowicz, PT Nelson… - Current …, 2011 - ingentaconnect.com
Amyloidopathies cause neurodegeneration in a substantial portion of the elderly population.
Improvements in long term health care have made elderly individuals a large and growing …