The current and potential therapeutic use of metformin—the good old drug

J Drzewoski, M Hanefeld - Pharmaceuticals, 2021 - mdpi.com
Metformin, one of the oldest oral antidiabetic agents and still recommended by almost all
current guidelines as the first-line treatment for type 2 diabetes mellitus (T2DM), has become …

Metformin: an old but still the best treatment for type 2 diabetes

LBA Rojas, MB Gomes - Diabetology & metabolic syndrome, 2013 - Springer
The management of T2DM requires aggressive treatment to achieve glycemic and
cardiovascular risk factor goals. In this setting, metformin, an old and widely accepted first …

Metformin: a review of its potential indications

YW Wang, SJ He, X Feng, J Cheng… - Drug design …, 2017 - Taylor & Francis
Metformin is the most commonly prescribed drug for type 2 diabetes mellitus. In recent years,
in addition to glucose lowering, several studies have presented evidence suggesting some …

Metformin: A review of potential mechanism and therapeutic utility beyond diabetes

S Dutta, RB Shah, S Singhal, SB Dutta… - Drug Design …, 2023 - Taylor & Francis
Metformin has been designated as one of the most crucial first-line therapeutic agents in the
management of type 2 diabetes mellitus. Primarily being an antihyperglycemic agent …

Metformin and its benefits for various diseases

Z Lv, Y Guo - Frontiers in endocrinology, 2020 - frontiersin.org
Metformin is a widely used biguanide drug due to its safety and low cost. It has been used
for over 60 years to treat type 2 diabetes at the early stages because of its outstanding ability …

Metformin in therapeutic applications in human diseases: Its mechanism of action and clinical study

Y Du, YJ Zhu, YX Zhou, J Ding, JY Liu - Molecular Biomedicine, 2022 - Springer
Metformin, a biguanide drug, is the most commonly used first-line medication for type 2
diabetes mellites due to its outstanding glucose-lowering ability. After oral administration of …

[HTML][HTML] Metformin and its clinical use: new insights for an old drug in clinical practice

AFG Cicero, E Tartagni, S Ertek - Archives of medical science: AMS, 2012 - ncbi.nlm.nih.gov
Metformin is generally recommended as first-line treatment in type 2 diabetes, especially in
overweight patients, but in recent years new indications for its use have emerged. Metformin …

Metformin revisited: re‐evaluation of its properties and role in the pharmacopoeia of modern antidiabetic agents

MO Goodarzi, M Bryer‐Ash - Diabetes, Obesity and …, 2005 - Wiley Online Library
Background: The usefulness of metformin as an oral antidiabetic agent is widely accepted.
However, several other classes of oral antidiabetic agents have been recently introduced …

[图书][B] Metformin-The gold standard: a scientific handbook

CJ Bailey, IW Campbell, JCN Chan, JA Davidson… - 2007 - research.aston.ac.uk
Metformin - The gold standard: a scientific handbook — Aston Research Explorer Skip to
main navigation Skip to search Skip to main content Aston Research Explorer Home Aston …

[HTML][HTML] Metformin: Is it a drug for all reasons and diseases?

CR Triggle, I Mohammed, K Bshesh, I Marei, K Ye… - Metabolism, 2022 - Elsevier
Metformin was first used to treat type 2 diabetes in the late 1950s and in 2022 remains the
first-choice drug used daily by approximately 150 million people. An accumulation of …