Amphiphilic dendritic derivatives as nanocarriers for the targeted delivery of antimalarial drugs

J Movellan, P Urbán, E Moles, JM de la Fuente… - Biomaterials, 2014 - Elsevier
It can be foreseen that in a future scenario of malaria eradication, a varied armamentarium
will be required, including strategies for the targeted administration of antimalarial …

Micelle carriers based on dendritic macromolecules containing bis-MPA and glycine for antimalarial drug delivery

EM Coma-Cros, A Lancelot, M San Anselmo… - Biomaterials …, 2019 - pubs.rsc.org
Biomaterials for antimalarial drug transport still need to be investigated in order to attain
nanocarriers that can tackle essential issues related to malaria treatment, eg complying with …

[HTML][HTML] Zwitterionic self-assembled nanoparticles as carriers for Plasmodium targeting in malaria oral treatment

A Biosca, P Cabanach, M Abdulkarim… - Journal of Controlled …, 2021 - Elsevier
The current decline in antimalarial drug efficacy due to the evolution of resistant Plasmodium
strains calls for new strategies capable of improving the bioavailability of antimalarials …

Promising nanomaterials in the fight against malaria

LN Borgheti-Cardoso, M San Anselmo… - Journal of Materials …, 2020 - pubs.rsc.org
For more than one hundred years, several treatments against malaria have been proposed
but they have systematically failed, mainly due to the occurrence of drug resistance in part …

Application of dendrimers for treating parasitic diseases

V Folliero, C Zannella, A Chianese, D Stelitano… - Pharmaceutics, 2021 - mdpi.com
Despite advances in medical knowledge, parasitic diseases remain a significant global
health burden and their pharmacological treatment is often hampered by drug toxicity …

Heparin-coated Dendronized Hyperbranched polymers for antimalarial targeted delivery

M San Anselmo, E Lantero… - ACS Applied Polymer …, 2022 - ACS Publications
The rampant evolution of resistance in Plasmodium to all existing antimalarial drugs calls for
the development of improved therapeutic compounds and of adequate targeted delivery …

PEGylated peptide dendrimeric carriers for the delivery of antimalarial drug chloroquine phosphate

D Bhadra, S Bhadra, NK Jain - Pharmaceutical research, 2006 - Springer
Purpose The present study was aimed at developing and exploring the use of uncoated and
chondroitin sulfate A (CSA) coated PEGylated poly-l-lysine-based dendrimers for controlled …

Nanomimics of host cell membranes block invasion and expose invasive malaria parasites

A Najer, D Wu, A Bieri, F Brand, CG Palivan, HP Beck… - ACS …, 2014 - ACS Publications
The fight against most infectious diseases, including malaria, is often hampered by the
emergence of drug resistance and lack or limited efficacies of vaccines. Therefore, new …

Recent advances in targeting malaria with nanotechnology-based drug carriers

H Rashidzadeh, SJ Tabatabaei Rezaei… - Pharmaceutical …, 2021 - Taylor & Francis
Malaria, as one of the most common human infectious diseases, remains the greatest global
health concern, since approximately 3.5 billion people around the world, especially those in …

A nanovector with complete discrimination for targeted delivery to Plasmodium falciparum-infected versus non-infected red blood cells in vitro

P Urbán, J Estelrich, A Cortés… - Journal of controlled …, 2011 - Elsevier
Current administration methods of antimalarial drugs deliver the free compound in the blood
stream, where it can be unspecifically taken up by all cells, and not only by Plasmodium …