Using personalized prognosis in the treatment of relapsing multiple sclerosis: a practical guide

B Van Wijmeersch, HP Hartung, P Vermersch… - Frontiers in …, 2022 - frontiersin.org
The clinical course of multiple sclerosis (MS) is highly variable among patients, thus creating
important challenges for the neurologist to appropriately treat and monitor patient progress …

Early prognosis of multiple sclerosis

J Swanton, K Fernando, D Miller - Handbook of clinical neurology, 2014 - Elsevier
Establishing the prognosis for multiple sclerosis (MS) early in the disease course is critically
important for patients who develop this disease. Potentially, this information could be used to …

[HTML][HTML] Emerging approaches for validating and managing multiple sclerosis relapse

EA Mills, A Mirza, Y Mao-Draayer - Frontiers in Neurology, 2017 - frontiersin.org
The autoimmune disease multiple sclerosis (MS) is characterized by relapses in the majority
of patients. A definitive clinical diagnosis of relapse in MS can be complicated by the …

Reaching an evidence-based prognosis for personalized treatment of multiple sclerosis

D Rotstein, X Montalban - Nature Reviews Neurology, 2019 - nature.com
Personalized treatment is ideal for multiple sclerosis (MS) owing to the heterogeneity of
clinical features, but current knowledge gaps, including validation of biomarkers and …

Personalized medicine in multiple sclerosis: hope or reality?

T Derfuss - BMC medicine, 2012 - Springer
Personalized treatment is highly desirable in multiple sclerosis because it is an immensely
heterogeneous disease. This heterogeneity is seen in both the disease course and the …

Identifying progression in multiple sclerosis: new perspectives

M Filippi, P Preziosa, D Langdon… - Annals of …, 2020 - Wiley Online Library
The identification of progression in multiple sclerosis is typically retrospective. Given the
profound burden of progressive multiple sclerosis, and the recent development of effective …

[PDF][PDF] Biomarkers for multiple sclerosis

P Villoslada - Drug News Perspect, 2010 - researchgate.net
The pursuit of personalized medicine requires the development of biomarkers to predict
disease course, monitor disease evolution, stratify patient subgroups by disease activity and …

Multiple sclerosis: clinical aspects

J Oh, A Vidal-Jordana, X Montalban - Current opinion in …, 2018 - journals.lww.com
A number of recent advances have been made in the clinical diagnosis and prognostication
of multiple sclerosis patients. Future research will enable the development of more accurate …

Biomarkers of therapeutic response in multiple sclerosis: current status

VK Harris, SA Sadiq - Molecular diagnosis & therapy, 2014 - Springer
Multiple sclerosis (MS) is an autoimmune disease of unknown cause, in which chronic
inflammation drives multifocal demyelination of axons in both white and gray matter in the …

Two sides to every story: perspectives from four patients and a healthcare professional on multiple sclerosis disease progression

J Burtchell, K Fetty, K Miller, K Minden, D Kantor - Neurology and Therapy, 2019 - Springer
Multiple sclerosis (MS) is a chronic progressive disease and many patients transition from
an initial relapsing–remitting course to a secondary progressive pattern. Accurate …