Experimental models to study end-organ morbidity in sleep apnea: lessons learned and future directions
R Farré, I Almendros, MÁ Martínez-García… - International Journal of …, 2022 - mdpi.com
Sleep apnea (SA) is a very prevalent sleep breathing disorder mainly characterized by
intermittent hypoxemia and sleep fragmentation, with ensuing systemic inflammation …
intermittent hypoxemia and sleep fragmentation, with ensuing systemic inflammation …
Human experimental models: seeking to enhance multiscale research in sleep apnoea
Human experimental models: seeking to enhance multiscale research in sleep apnoea |
European Respiratory Society Skip to main content Main menu Home Current issue ERJ Early …
European Respiratory Society Skip to main content Main menu Home Current issue ERJ Early …
Cardiovascular consequences of sleep-disordered breathing: contribution of animal models to understanding of the human disease
M Dematteis, D Godin-Ribuot, C Arnaud, C Ribuot… - ILAR …, 2009 - academic.oup.com
Sleep-disordered breathing, and particularly the highly prevalent obstructive sleep apnea
syndrome, is a multicomponent disorder combining intermittent hypoxia (IH), sleep …
syndrome, is a multicomponent disorder combining intermittent hypoxia (IH), sleep …
[HTML][HTML] Intermittent hypoxia severity in animal models of sleep apnea
Obstructive sleep apnea (OSA) is a very prevalent breathing disorder (Peppard et al., 2013;
Heinzer et al., 2015) characterized by recurrent obstructions of the upper airway during …
Heinzer et al., 2015) characterized by recurrent obstructions of the upper airway during …
New frontiers in obstructive sleep apnoea
OSA (obstructive sleep apnoea), the most common respiratory disorder of sleep, is caused
by the loss of upper airway dilating muscle activity during sleep superimposed on a narrow …
by the loss of upper airway dilating muscle activity during sleep superimposed on a narrow …
Sleep apnea research in animals. Past, present, and future
Obstructive sleep apnea (OSA) is a common disorder that describes recurrent collapse of
the upper airway during sleep. Animal models have been pivotal to the understanding of …
the upper airway during sleep. Animal models have been pivotal to the understanding of …
Morbidity due to obstructive sleep apnea: insights from animal models
The simple experimental models used to investigate OSA morbidity are useful for
investigating isolated mechanisms. However, more complex and realistic models …
investigating isolated mechanisms. However, more complex and realistic models …
Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer
I Hunyor, KM Cook - American Journal of Physiology …, 2018 - journals.physiology.org
Obstructive sleep apnea (OSA) is common and linked to a variety of poor health outcomes. A
key modulator of this disease is nocturnal intermittent hypoxia. There is striking …
key modulator of this disease is nocturnal intermittent hypoxia. There is striking …
Advanced concepts in the pathophysiology of obstructive sleep apnea
DP White - Sleep-Related Breathing Disorders, 2017 - karger.com
The primary pathological event in the disorder obstructive sleep apnea (OSA) is the partial
or complete closure of the pharyngeal airway during sleep in an individual with a widely …
or complete closure of the pharyngeal airway during sleep in an individual with a widely …
Biological plausibility linking sleep apnoea and metabolic dysfunction
A Gileles-Hillel, L Kheirandish-Gozal… - Nature Reviews …, 2016 - nature.com
Obstructive sleep apnoea (OSA) is a very common disorder that affects 10–25% of the
general population. In the past two decades, OSA has emerged as a cardiometabolic risk …
general population. In the past two decades, OSA has emerged as a cardiometabolic risk …