Background Placenta-related obstetric complications (PROCs) such as miscarriage, fetal
growth restriction, preeclampsia, and preterm birth are the major causes of maternal and …

Plasminogen activator inhibitor type 1 (PAI-1) is a main inhibitor of fibrinolysis. The PAI-1
gene (SERPINE1) harbors genetic variants with the potential of modifying plasma levels of …

Human plasminogen activator inhibitor‐1 (PAI‐1) is closely related to embryonic
development and pregnancy success. The association between PAI‐1 gene polymorphisms …

METHODS: Our study included 83 hypertensive pregnant women (64 preeclamptic women,
12 pregnant women with HELLP syndrome, and 7 eclamptic women) genotyped for PAI-1 …

A dramatic change in most of the coagulation factors and natural inhibitors of coagulation
occurs in healthy pregnancy to enable the body to reduce hemorrhage during child birth …

Background and Aims Excessive generation of plasminogen activator inhibitor-type 1 (PAI-
1) is implicated in the pathogenesis of pre-eclampsia and related conditions. The PAI-1 …

Background: Despite pregnancy's hypercoagulable state, the correlation between inherited
thrombophilia and thrombotic adverse pregnancy outcomes remains uncertain. The …

Plasminogen activator inhibitor-1 (PAI-1) is important for maintaining pregnancy. Aberrantly
increased PAI-1 levels may contribute to thrombosis and inflammation, leading to pregnancy …

Abstract Aim: Plasminogen activator inhibitor-1 (PAI-1) is an important inhibitor of the
fibrinolytic system, so it is biologically plausible that elevated levels could suppress …

Meta-Analysis of the Association between Plasminogen Activator Inhibitor-1 4G/5G
Polymorphism and Recurrent Pregnancy Loss - PMC Back to Top Skip to main content NIH NLM …