About half of the world's population and 80% of the world's biodiversity can be found in the
tropics. Many diseases are specific to the tropics, with at least 41 diseases caused by …

Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in developing …

New chemical entities are desperately needed that overcome the limitations of existing
drugs for neglected diseases. Screening a diverse library of 10,000 drug-like compounds …

Collaborations between academic, industrial, and nonprofit companies can provide
sufficient impetus to propel projects that have little economic return; such projects are …

Covering: up to 2019 Secondary metabolites of microbial origin have long been
acknowledged as medically relevant, but their full potential remains largely unexploited. Of …

Infectious diseases still one of the major causes of mortality and morbidity worldwide. The
incidences of these infections are higher in communities exposed to inadequate sanitary …

Infectious tropical diseases have a huge effect in terms of mortality and morbidity, and
impose a heavy economic burden on affected countries. These diseases predominantly …

Antibiotics have revolutionised medicine in many aspects, and their discovery is considered
a turning point in human history. However, the most serious consequence of the use of …

The continued spread of antimicrobial resistance represents one of the most serious
infectious disease threats to global health. There is consensus that a key component of …

Drug development for neglected tropical diseases, defined as a collection of infectious
diseases affecting over 4 billion people worldwide (especially endemic to poverty-stricken …