NKT cells represent a distinct lineage of T cells that coexpress a conserved αβ T cell
receptor (TCR) and natural killer (NK) receptors. Although the TCR of NKT cells is …

Natural killer T (NKT) cells constitute a highly conserved T lymphocyte subpopulation that
has the potential to regulate many types of immune responses through the rapid secretion of …

CD1d-restricted natural killer T (NKT) cells are innate-like lymphocytes that express a
conserved T-cell receptor and contribute to host defence against various microbial …

Natural killer T (NKT) lymphocytes express an invariant T cell antigen receptor (TCR)
encoded by the Vα14 and Jα281 gene segments. A glycosylceramide-containing α …

Experimental autoimmune encephalomyelitis (EAE) is a prototype autoimmune disease
mediated by type 1 helper T (TH1) cells and under the control of regulatory cells,,. Here we …

The most potent foreign antigens for natural killer T cells (NKT cells) are α-linked glycolipids,
whereas NKT cell self-reactivity involves weaker recognition of structurally distinct β-linked …

Development of invariant natural killer T (iNKT) cells requires the presentation of lipid ligand
(s) by CD1d molecules in the thymus. The glycosphingolipid (GSL) …

CD1d-restricted natural killer T (NKT) cells are a subset of regulatory T cells that react with
glycolipid antigens. Although preclinical studies have effectively targeted NKT cells for …

Immunoglobulin G (IgG) responses require major histocompatibility complex (MHC)–
restricted recognition of peptide fragments by conventional CD4+ helper T cells …

CD1d-restricted natural killer T (NKT) cells, expressing the invariant T cell antigen receptor
(TCR) chain encoded by Vα14-Jα18 gene segments in mice and Vα24-Jα18 in humans …