Progression of HPV infection to detectable cervical lesions or clearance in adult women: Analysis of the control arm of the VIVIANE study

S Rachel Skinner, CM Wheeler… - … journal of cancer, 2016 - Wiley Online Library
The control arm of the phase III VIVIANE (Human PapillomaVIrus: Vaccine Immunogenicity
ANd Efficacy; NCT00294047) study in women> 25 years was studied to assess risk of …

Incident cervical HPV infections in young women: transition probabilities for CIN and infection clearance

RP Insinga, G Perez, CM Wheeler, LA Koutsky… - … Biomarkers & Prevention, 2011 - AACR
Background: We describe transition probabilities for incident human papillomavirus (HPV)
16/18/31/33/35/45/52/58/59 infections and cervical intraepithelial neoplasia (CIN) 1 lesions …

Persistence of HPV infection and risk of high-grade cervical intraepithelial neoplasia in a cohort of Colombian women

N Muñoz, G Hernandez-Suarez, F Mendez… - British journal of …, 2009 - nature.com
Little is known about the dynamics of human papillomavirus (HPV) infection and subsequent
development of high-grade cervical intraepithelial neoplasia (CIN2/3), particularly in …

Rapid clearance of human papillomavirus and implications for clinical focus on persistent infections

AC Rodríguez, M Schiffman, R Herrero… - Journal of the …, 2008 - academic.oup.com
Health professionals and the public need to understand the natural history of human
papillomavirus (HPV) infections of the cervix to best use the information provided by new …

Risk of high‐grade precancerous lesions and invasive cancers in high‐risk HPV‐positive women with normal cervix or CIN 1 at baseline—A population‐based cohort …

S Mittal, P Basu, R Muwonge… - … journal of cancer, 2017 - Wiley Online Library
Infection with high‐risk human papillomavirus (HR‐HPV) is transient and clears on its own in
majority of the women. Only a few women who have persistent infection may finally develop …

Persistence of an incident human papillomavirus infection and timing of cervical lesions in previously unexposed young women

H Trottier, SM Mahmud, L Lindsay, D Jenkins… - … Biomarkers & Prevention, 2009 - AACR
Background: We analyzed data from a cohort of 553 women enrolled in the placebo arm of a
randomized controlled trial of the human papillomavirus (HPV) 16/18 vaccine to study the …

The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the possible utility of type-specific HPV …

MJ Khan, PE Castle, AT Lorincz… - Journal of the …, 2005 - academic.oup.com
Background: Human papillomavirus (HPV) types 16 and 18 cause 60%–70% of cervical
cancer worldwide, and other HPV types cause virtually all remaining cases. Pooled HPV …

Natural history of progression of HPV infection to cervical lesion or clearance: analysis of the control arm of the large, randomised PATRICIA study

U Jaisamrarn, X Castellsague, SM Garland, P Naud… - PloS one, 2013 - journals.plos.org
Background The control arm of PATRICIA (PApillomaTRIal against Cancer In young Adults,
NCT00122681) was used to investigate the risk of progression from cervical HPV infection to …

Long-term absolute risk of cervical intraepithelial neoplasia grade 3 or worse following human papillomavirus infection: role of persistence

SK Kjær, K Frederiksen, C Munk… - Journal of the National …, 2010 - academic.oup.com
Background Infection with high-risk human papillomavirus (HPV) is the main cause of high-
grade cervical intraepithelial neoplasia (CIN) and cancer. It has been suggested that …

Persistence of type-specific human papillomavirus infection and increased long-term risk of cervical cancer

HC Chen, M Schiffman, CY Lin, MH Pan… - Journal of the …, 2011 - academic.oup.com
Background Human papillomavirus (HPV) persistence is the pivotal event in cervical
carcinogenesis. We followed a large-scale community-based cohort for 16 years to …