The six mammalian glycosaminoglycans (GAGs), chondroitin sulfate, dermatan sulfate,
heparin, heparan sulfate, hyaluronan, and keratan sulfate, are linear polysaccharides …

Glycosaminoglycans (GAGs) are complex linear polysaccharides, which are covalently
attached to core proteins (except for hyaluronan) to form proteoglycans. They play key roles …

Glycosaminoglycans (GAGs) are a family of linear and negatively charged polysaccharides
that exist ubiquitously on the human cell surface as well as in the extracellular matrix. GAGs …

The extracellular environment is largely comprised of complex polysaccharides, which were
historically considered inert materials that hydrated the cells and contributed to the structural …

Highlights•Binding of proteins to glycosaminoglycans regulates development and
homeostasis.•Saccharide charge distribution, dynamics and conformation determine protein …

Glycosaminoglycans are complex polysaccharides exhibiting a large structural and
conformational diversity. These key biological players organize the extracellular matrix …

The past decade has seen an explosion of information about proteoglycans (PGs). We now
know that there are multiple classes of core proteins that carry cell surface heparan sulfate …

Glycosaminoglycans (GAGs) are heterogeneous, negatively charged, macromolecules that
are found in animal tissues. Based on the form of component sugar, GAGs have been …

Glycosaminoglycan polysaccharides play critical roles in many cellular processes, ranging
from viral invasion and angiogenesis to spinal cord injury. Their diverse biological activities …

Glycosaminoglycans (GAGs) are complex polysaccharides exhibiting a vast structural
diversity and fulfilling various functions mediated by thousands of interactions in the …