Host genetics of cytomegalovirus pathogenesis

E Sezgin, P An, CA Winkler - Frontiers in genetics, 2019 - frontiersin.org
Human cytomegalovirus (HCMV) is a ubiquitous herpes virus (human herpes virus 5) with
the highest morbidity and mortality rates compared to other herpes viruses. Risk groups …

Functional profile of human cytomegalovirus genes and their associated diseases: a review

L Ye, Y Qian, W Yu, G Guo, H Wang, X Xue - Frontiers in microbiology, 2020 - frontiersin.org
The human cytomegalovirus (HCMV), whose genome is 235±1.9 kbp long, is a common
herpesvirus. However, the functions of many of its genes are still unknown. HCMV is closely …

The interplay between host and viral factors in shaping the outcome of cytomegalovirus infection

AA Scalzo, AJ Corbett, WD Rawlinson… - Immunology and cell …, 2007 - Wiley Online Library
Cytomegalovirus (CMV) remains a major human pathogen causing significant morbidity and
mortality in immunosuppressed or immunoimmature individuals. Although significant …

Common polymorphisms in the glycoproteins of human cytomegalovirus and associated strain-specific immunity

HY Wang, SM Valencia, SP Pfeifer, JD Jensen… - Viruses, 2021 - mdpi.com
Human cytomegalovirus (HCMV), one of the most prevalent viruses across the globe, is a
common cause of morbidity and mortality for immunocompromised individuals. Recent …

Human cytomegalovirus latent infection and associated viral gene expression

B Slobedman, JZ Cao, S Avdic, B Webster… - Future …, 2010 - Taylor & Francis
Human cytomegalovirus (HCMV) is a clinically important and ubiquitous herpesvirus.
Following primary productive infection the virus is not completely eliminated from the host …

Genetic polymorphisms among human cytomegalovirus (HCMV) wild‐type strains

S Pignatelli, PD Monte, G Rossini… - Reviews in medical …, 2004 - Wiley Online Library
Human cytomegalovirus (HCMV) clinical isolates display genetic polymorphisms in multiple
genes. Some authors have suggested that those polymorphisms may be implicated in …

Evolution and genetic diversity of primate cytomegaloviruses

R Cagliani, D Forni, A Mozzi, M Sironi - Microorganisms, 2020 - mdpi.com
Cytomegaloviruses (CMVs) infect many mammals, including humans and non–human
primates (NHPs). Human cytomegalovirus (HCMV) is an important opportunistic pathogen …

Molecular pathogenesis of human cytomegalovirus infection

L Rasmussen - Transplant infectious disease, 1999 - Wiley Online Library
Despite progress in diagnosis and treatment of human cytomegalovirus (CMV) infection, we
do not understand why, in hosts with comparable levels of immunosuppression, some CMV …

Human cytomegalovirus: an enormous variety of strains and their possible clinical significance in the human host

E Puchhammer-Stöckl, I Görzer - Future Virology, 2011 - Taylor & Francis
Human cytomegalovirus (HCMV) does not exist as one defined virus genotype, but as a
variety of different strains. Several studies have investigated the significance of specific viral …

Overview of human cytomegalovirus pathogenesis

HL Fulkerson, MT Nogalski, D Collins-McMillen… - … : Methods and Protocols, 2021 - Springer
Human cytomegalovirus (HCMV) is a betaherpesvirus with a global seroprevalence of 60–
90%. HCMV is the leading cause of congenital infections and poses a great health risk to …