A major challenge in ART is to select high-quality oocytes and embryos. The metabolism of
oocytes and embryos has long been linked to their viability, suggesting the potential utility of …

Current strategies for embryo assessment in the assisted reproductive technology
laboratories rely primarily on morphologic parameters that have limited accuracy for …

STUDY QUESTION Can non-invasive imaging with fluorescence lifetime imaging
microscopy (FLIM) detect metabolic differences in euploid versus aneuploid human …

STUDY QUESTION Can non-invasive metabolic imaging via fluorescence lifetime imaging
microscopy (FLIM) detect variations in metabolic profiles between discarded human …

Objective To determine whether metabolic imaging with the use of fluorescence lifetime
imaging microscopy (FLIM) identifies metabolic differences between normal oocytes and …

Oocyte quality is a key factor influencing IVF success. The oocyte and surrounding cumulus
cells, known collectively as the cumulus oocyte complex (COC), communicate bi …

Oocyte developmental potential is intimately linked to metabolism. Existing approaches to
measure metabolism in the cumulus oocyte complex (COC) do not provide information on …

STUDY QUESTION Is the combined use of fluorescence lifetime imaging microscopy (FLIM)-
based metabolic imaging and second harmonic generation (SHG) spindle imaging a …

Objective To determine whether fluorescence lifetime imaging microscopy (FLIM) detects
differences in metabolic state among cumulus cell samples and whether their metabolic …

BACKGROUND Within the antral follicle, the oocyte is reliant on metabolic support from its
surrounding somatic cells. Metabolism plays a critical role in oocyte developmental …