Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

JA Dani, D Bertrand - Annu. Rev. Pharmacol. Toxicol., 2007 - annualreviews.org
Subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) are constructed from
numerous subunit combinations that compose channel-receptor complexes with varied …

Structural and functional diversity of native brain neuronal nicotinic receptors

C Gotti, F Clementi, A Fornari, A Gaimarri… - Biochemical …, 2009 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand-gated ion
channels present in the central and peripheral nervous systems, that are permeable to mono …

Overview of nicotinic receptors and their roles in the central nervous system

JA Dani - Biological psychiatry, 2001 - Elsevier
Alzheimer's disease is a complex disorder affecting multiple neurotransmitters. In particular,
the degenerative progression is associated with loss within the cholinergic systems. It …

Molecular diversity of neuronal nicotinic acetylcholine receptors

DS McGEHEE - Annals of the New York Academy of Sciences, 1999 - Wiley Online Library
The potent behavioral and cognitive effects of nicotine highlight the physiological
importance of nicotinic acetylcholine receptors (nAChRs). These receptors are part of the …

[HTML][HTML] Nicotinic acetylcholine receptors in neurological and psychiatric diseases

AV Terry Jr, K Jones, D Bertrand - Pharmacological Research, 2023 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that are
widely distributed both pre-and post-synaptically in the mammalian brain. By modulating …

Human neuronal nicotinic receptors

C Gotti, D Fornasari, F Clementi - Progress in neurobiology, 1997 - Elsevier
Nicotine is a very widely used drug of abuse, which exerts a number of neurovegetative,
behavioural and psychological effects by interacting with neuronal nicotinic acetylcholine …

Brain nicotinic acetylcholine receptors: native subtypes and their relevance

C Gotti, M Zoli, F Clementi - Trends in pharmacological sciences, 2006 - cell.com
Neuronal nicotinic acetylcholine receptors comprise a heterogeneous class of cationic
channels that is present throughout the nervous system. These channels are involved both …

Nicotine, brain nicotinic receptors, and neuropsychiatric disorders

S Mihailescu, R Drucker-Colı́n - Archives of medical research, 2000 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) represent a large family of ligand-
gated cation channels with diverse structures and properties. In contrast to the muscular …

Nicotinic acetylcholine receptors: Conventional and unconventional ligands and signaling

RL Papke, JM Lindstrom - Neuropharmacology, 2020 - Elsevier
Postsynaptic nAChRs in the peripheral nervous system are critical for neuromuscular and
autonomic neurotransmission. Pre-and peri-synaptic nAChRs in the brain modulate …

Neuronal nicotinic acetylcholine receptor structure and function and response to nicotine

JA Dani - International review of neurobiology, 2015 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) belong to the “Cys-loop” superfamily of ligand-
gated ion channels that includes GABA A, glycine, and serotonin (5-HT 3) receptors. There …