With the insufficient satisfaction rates and high cost of operative treatment for osteoarthritis
(OA), alternatives have been sought. Furthermore, the inability of current medications to …

The prevalence of osteoarthritis (OA), a degenerative disorder of joints, has substantially
increased in recent years. Its key pathogenic hallmarks include articular cartilage …

Osteoarthritis (OA) is a multifaceted disease characterized by imbalances in extracellular
matrix metabolism, chondrocyte and synoviocyte senescence, as well as inflammatory …

As the most common form of joint disorder, osteoarthritis (OA) imposes a tremendous burden
on health care systems worldwide. Without effective cure, OA represents a unique …

Osteoarthritis (OA) is a chronic joint disease that generally occurs worldwide with pain and
disability. The progression is slow, and it is mostly diagnosed midlife and often disturbs the …

Osteoarthritis (OA) is a painful chronic condition with a significant impact on quality of life.
The societal burden imposed by OA is increasing in parallel with the aging population; …

Osteoarthritis (OA) is a chronic, prevalent, debilitating joint disease characterized by
progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions …

Osteoarthritis (OA) has traditionally been known as a “wear and tear” disease, which is
mainly characterized by the degradation of articular cartilage and changes in the …

Osteoarthritis (OA) is an inflammatory condition still lacking effective treatments.
Mesenchymal stem/stromal cells (MSCs) have been successfully employed in pre-clinical …

Osteoarthritis is a leading cause of pain and disability across the world. With an aging
population its prevalence is likely to further increase. Current accepted medical treatment …