Astilbin selectively induces dysfunction of liver-infiltrating cells—novel protection from liver damage
Q Xu, F Wu, J Cao, T Chen, J Jiang, I Saiki… - European Journal of …, 1999 - Elsevier
The present study aimed to examine the effect of astilbin, a flavanoid, on liver injury. When
administered during the effector but not induction phase, astilbin significantly decreased the …
administered during the effector but not induction phase, astilbin significantly decreased the …
Astilbin prevents concanavalin A-induced liver injury by reducing TNF-α production and T lymphocyte adhesion
J Wang, Y Zhao, Q Xu - Journal of Pharmacy and Pharmacology, 2004 - academic.oup.com
The aim of this study was to evaluate the effect of astilbin on concanavalin A (Con A)-
induced hepatitis, a T cell-dependent model of liver injury. Con A administration resulted in a …
induced hepatitis, a T cell-dependent model of liver injury. Con A administration resulted in a …
Effect of indole‐3‐carbinol on ethanol‐induced liver injury and acetaldehyde‐stimulated hepatic stellate cells activation using precision‐cut rat liver slices
Y Guo, XQ Wu, C Zhang, ZX Liao, Y Wu… - Clinical and …, 2010 - Wiley Online Library
Indole‐3‐carbinol (I3C), a major indole compound found in high levels in cruciferous
vegetables, shows a broad spectrum of biological activities. However, few studies have …
vegetables, shows a broad spectrum of biological activities. However, few studies have …
Tanshinone IIA protects against immune-mediated liver injury through activation of T-cell subsets and regulation of cytokines
XY Qin, T Li, L Yan, QS Liu, Y Tian - Immunopharmacology and …, 2010 - Taylor & Francis
Background and Aim: Tanshione IIA (TSN) is the major active component of Salvia
miltiorrhiza, a traditional Chinese Medicine. TSN protects against antioxidant-induced liver …
miltiorrhiza, a traditional Chinese Medicine. TSN protects against antioxidant-induced liver …
The protective effect of the natural compound hesperetin against fulminant hepatitis in vivo and in vitro
X Bai, P Yang, Q Zhou, B Cai… - British Journal of …, 2017 - Wiley Online Library
Background and Purpose Liver diseases are mostly accompanied by inflammation and
hepatocyte death. Therapeutic approaches targeting both hepatocyte injury and …
hepatocyte death. Therapeutic approaches targeting both hepatocyte injury and …
Allicin attenuated hepatic ischemia/reperfusion injury in mice by regulating PPARγ-IRAK-M-TLR4 signal pathway
W Li, R Huang, X Gong, Z Zhao, L Zhang, Q Zhou… - Food & Function, 2022 - pubs.rsc.org
Background: Hepatic ischemia/reperfusion (I/R) injury to the liver is a significant cause of
morbidity and mortality following liver surgery, trauma, and hemorrhagic shock. It was …
morbidity and mortality following liver surgery, trauma, and hemorrhagic shock. It was …
Fumigaclavine C improves concanavalin A‐induced liver injury in mice mainly via inhibiting TNF‐α production and lymphocyte adhesion to extracellular matrices
Fumigaclavine C, an alkaloidal metabolite, was produced by Aspergillus fumigatus (strain
No. CY018). This study examined the effect of this compound on concanavalin A (Con A) …
No. CY018). This study examined the effect of this compound on concanavalin A (Con A) …
Antihepatotoxic Effect of Tadehaginoside, Extracted from Tadehagi triquetrum (L.), Against CCl4-Lesioned Rats Through Activating the Nrf2 Signaling Pathway and …
A Tang, X Chen, Q Lu, N Zheng, Y Wei, X Wu - Inflammation, 2014 - Springer
Recently, an increasing number of studies suggest that oxidative stress and inflammation
are associated with hepatocellular injuries. Thus, we aimed to evaluate the potential …
are associated with hepatocellular injuries. Thus, we aimed to evaluate the potential …
Silibinin protects mice from T cell-dependent liver injury☆
J Schümann, J Prockl, AK Kiemer, AM Vollmar… - Journal of …, 2003 - Elsevier
Background/Aims: Silibinin is the major pharmacologically active compound of the Silybum
marianum fruit extract silymarin. Its well-known hepatoprotective activities are mostly …
marianum fruit extract silymarin. Its well-known hepatoprotective activities are mostly …
Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts
EJ Park, YZ Zhao, YC Kim, DH Sohn - European journal of pharmacology, 2007 - Elsevier
Liver fibrosis and cirrhosis may be reversible, possibly through the selective clearance of
activated hepatic stellate cells/myofibroblasts by apoptosis. Hepatic stellate cells …
activated hepatic stellate cells/myofibroblasts by apoptosis. Hepatic stellate cells …