The D3 dopamine receptor: neurobiology and potential clinical relevance

B Levant - Pharmacological reviews, 1997 - ASPET
Dopamine is a major neurotransmitter in the central nervous system. Receptors for this
catecholamine are of considerable interest, as they are the principal target of drugs …

The D3 dopamine receptor in cellular and organismal function

RA Shafer, B Levant - Psychopharmacology, 1998 - Springer
The D 3 dopamine receptor is a member of the family of D 2-like dopamine receptors. Since
the cloning and identification of the D 3 receptor in 1990, considerable progress has been …

The dopamine D4 receptor: one decade of research

JN Oak, J Oldenhof, HHM Van Tol - European journal of pharmacology, 2000 - Elsevier
Dopamine is an important neurotransmitter involved in motor control, endocrine function,
reward, cognition and emotion. Dopamine receptors belong to the superfamily of G protein …

Dopamine D3 receptor as a therapeutic target for antipsychotic and antiparkinsonian drugs

JN Joyce - Pharmacology & therapeutics, 2001 - Elsevier
The cloning of the gene for the D3 receptor and subsequent identification of its distribution in
brain and pharmacology allowed for serious consideration of the possibility that it might be a …

Expression and pharmacological characterization of the human D3 dopamine receptor.

SB Freedman, S Patel, R Marwood, F Emms… - … of Pharmacology and …, 1994 - ASPET
Binding of dopamine receptor ligands to human D2 and D3 receptors was characterized in
Chinese hamster ovary (CHO) cells using the dopamine D2 receptor antagonist [125I] …

The D1 dopamine receptor in the rat brain: quantitative autoradiographic localization using an iodinated ligand

TM Dawson, P Barone, A Sidhu, JK Wamsley… - Neuroscience, 1988 - Elsevier
The distribution of dopamine D 1 receptors in the rat, labeled with [125 I] SCH 23982, was
studied using a quantitative in-vitro light-microscopic autoradiographic method. The binding …

Dopamine receptors: molecular biology, biochemistry and behavioural aspects

DM Jackson, A Westlind-Danielsson - Pharmacology & therapeutics, 1994 - Elsevier
The description of new dopamine (DA) receptor subtypes, D1-(D1 and D5) and D2-like
(D2A, D2B, D3, D4), has given an impetus to DA research. While selective agonists and …

Progress in developing D3 dopamine receptor ligands as potential therapeutic agents for neurological and neuropsychiatric disorders

RR Luedtke, RH Mach - Current pharmaceutical design, 2003 - ingentaconnect.com
The dopamine D3 receptor has been the subject of a tremendous amount of research since
its discovery in 1990. A previous review of this subject [3] described the advances in …

Brain dopamine receptors: a primer on their current status, basic and clinical

RJ Baldessarini, FI Tarazi - Harvard review of psychiatry, 1996 - Taylor & Francis
Recent progress in understanding the molecular biology and pharmacology of dopamine
receptors in mammalian brain has been remarkable and can serve as a basis for …

The D-1 dopamine receptor and the search for its functional role: from neurochemistry to behaviour

JL Waddington, KM O'Boyle - Reviews in the Neurosciences, 1987 - degruyter.com
The recent impact of new drugs acting selectively on Dl dopamine receptors is reviewed. l-
phenyl-lH-3-benzazepines, typified by SCH 23390, SK&F 83566 and SK&F 38393 …