In addition to its role as a neuronal energy substrate and signaling molecule involved in
synaptic plasticity and memory consolidation, recent evidence shows that lactate produces …

In addition to its role as metabolic substrate that can sustain neuronal function and viability,
emerging evidence supports a role for l-lactate as an intercellular signaling molecule …

Although antipsychotics that act via monoaminergic neurotransmitter modulation have
considerable therapeutic effect, they cannot completely relieve clinical symptoms in patients …

l‐Lactate is emerging as a crucial regulatory nexus for energy metabolism in the brain and
signaling transduction in synaptic plasticity, memory processes, and drug addiction instead …

ABSTRACT The endocannabinoid ligand 2‐arachidonoylglycerol (2‐AG) is inactivated
primarily by monoacylglycerol lipase (MAGL). We have shown recently that chronic …

l-lactate is a product of aerobic glycolysis that can be used by neurons as an energy
substrate. Here we report that in neurons l-lactate stimulates the expression of synaptic …

Experimental evidence has demonstrated that glutamate is an essential factor for
neurogenesis, whereas another line of research postulates that excessive glutamatergic …

Chronic stress promotes depression in some individuals, but has no effect in others.
Susceptible individuals exhibit social avoidance and anxious behavior and ultimately …

Adult hippocampal neurogenesis is affected in some neuropsychiatric disorders such as
depression. Numerous evidence indicates that plasma levels of melatonin are decreased in …

Lactate, a product of aerobic glycolysis in astrocytes, is required for memory formation and
consolidation, and has recently emerged as a signaling molecule for neurons and various …