Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by inflammatory
back pain and spinal ankylosis due to pathological new bone formation. Here, we identified …

Background Ankylosing spondylitis (AS) is an autoimmune disease with a genetic
correlation and is characterized by inflammation in the axial skeleton and sacroiliac joints …

Ankylosing spondylitis (AS) is a common inflammatory autoimmune disease, characterized
by pathological osteogenesis. Mesenchymal stem cells (MSCs), as the main source of …

Ankylosing spondylitis (AS) is a type of axial inflammation. Over time, some patients develop
spinal ankylosis and permanent disability; however, current treatment strategies cannot …

Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by pathological
osteogenesis and inflammation. However, the pathogenesis of AS and the pathological …

Pathological new bone formation is a typical pathological feature in ankylosing spondylitis
(AS), and the underlying molecular mechanism remains elusive. Previous studies have …

Bony fusion caused by pathological new bone formation manifests the clinical feature of
ankylosing spondylitis (AS). However, the underlying mechanism remains elusive. Here we …

Ankylosing spondylitis (AS) is chronic inflammatory arthritis with a progressive fusion of axial
joints. Anti-inflammatory treatments such as anti-TNF-α antibody therapy suppress …

The mechanism of pathological osteogenesis in Ankylosing spondylitis (AS) is largely
unknown. Our previous studies demonstrated that the imbalance between BMP-2 and …

Generalized osteoporosis is common in patients with inflammatory diseases, possibly
because of circulating inflammatory factors that affect osteoblast and osteoclast formation …