Foreign particles and apoptotic bodies are eliminated from the body by phagocytic
leucocytes. The initial stage of the elimination process is the internalization of the particles …

Phagocytosis mediates the clearance of apoptotic bodies and also the elimination of
microbial pathogens. The nascent phagocytic vacuole formed upon particle engulfment …

Phagosome maturation is the process by which internalized particles (such as bacteria and
apoptotic cells) are trafficked into a series of increasingly acidified membrane-bound …

Phagocytosis, the regulated uptake of large particles (> 0.5 μm in diameter), is essential for
tissue homeostasis and is also an early, critical component of the innate immune response …

Cells of the innate immune system ingest and destroy invading microorganisms by initially
engulfing them into a specialized vacuole, known as the phagosome. The membrane of the …

Phagocytosis is essential for the elimination of pathogens and for clearance of apoptotic
bodies. The ingestion process entails extensive remodeling of the cellular membranes …

Engulfment and destruction of invading microorganisms by phagocytosis are critical
components of the innate immune response. In addition, phagocytosis is also required for …

Phagocytosis is defined as the receptor-mediated engulfment of large (≥ 0.5 μm) particles
into plasma membrane-derived vacuoles called phagosomes. Following scission from the …

Nascent phagosomes, which are derived from the plasma membrane, acquire microbicidal
properties through multiple fusion and fission events collectively known as maturation. Here …

Maturation of phagosomes is characterized by changes in their polypeptides,
phosphorylated proteins and phospholipid composition. Kinetic analyses have shown that a …