An important part of the central nervous system (CNS), the cerebellum is involved in motor
control, learning, reflex adaptation, and cognition. Diminished cerebellar function results in …

As a large and heterogeneous group of disorders, neurodegenerative diseases are
characterized by the progressive loss of structure or function in neurons, finally leading to …

Aging is a natural phenomenon that occurs due to a variety of loosely understood
mechanisms [1]. Under physiological conditions, cells defend themselves through their …

According to Alzheimer's Disease International, 55 million people worldwide are living with
dementia. Dementia is a disorder that manifests as a set of related symptoms, which usually …

Aging is a major risk factor for many human diseases, including cognitive impairment, which
affects a large population of the elderly. In the past few decades, our understanding of the …

The process of ageing is characteristic of multicellular organisms associated with late stages
of the lifecycle and is manifested through a plethora of phenotypes. Its underlying …

Brain aging causes a wide variety of changes at the molecular and cellular levels, leading to
the decline of cognitive functions and increased vulnerability to neurodegenerative …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the primary diseases in
neurodegenerative diseases. Nowadays, AD is common in one of the ten individuals whose …

Aging is accompanied by many changes in brain and contributes to progressive cognitive
decline. In contrast to pathological changes in brain, normal aging brain changes have …

Epigenetic changes are changes in gene expression that do not involve alterations to the
DNA sequence. These changes lead to establishing a so-called epigenetic code that …