Opioid use during pregnancy continues to rise at alarming rates with a parallel trend in the
number of infants and children exposed to opioid medications each year. Prenatal opioid …

The increased incidence of opioid use during pregnancy warrants investigation to reveal the
impact of opioid exposure on the developing fetus. Exposure during critical periods of …

The rates of opioid use disorder during pregnancy have more than quadrupled in the last
decade, resulting in numerous infants suffering exposure to opioids during the perinatal …

Substance use, specifically the use of prescription and non-prescription opioids among
pregnant women, is a major public health issue and chief contributor to the opioid crisis. The …

The opioid epidemic has received considerable attention, but the impact on perinatal opioid-
exposed (POE) offspring remains underexplored. This study addresses the emerging public …

The opioid epidemic is an ongoing public health crisis, and children born following prenatal
opioid exposure (POE) have increased risk of long-term cognitive and behavioral sequelae …

Background Preclinical data demonstrate that opioids modulate brain reward signaling
through an inflammatory cascade, but this relationship has yet to be studied in opioid …

As problematic opioid use has reached epidemic levels over the past 2 decades, the annual
prevalence of opioid use disorder (OUD) in pregnant women has also increased 333%. Yet …

Perinatal exposure to prescription opioids pose a critical public health risk. Notably,
research has found significant neurodevelopmental and behavioral deficits between in utero …

As a result of the current opioid crisis, the rate of children born exposed to opioids has
skyrocketed. Later in life, these children have an increased risk for hospitalization and …