Tether-free photothermal deep-brain stimulation in freely behaving mice via wide-field illumination in the near-infrared-II window

X Wu, Y Jiang, NJ Rommelfanger, F Yang… - Nature Biomedical …, 2022 - nature.com
Neural circuitry is typically modulated via invasive brain implants and tethered optical fibres
in restrained animals. Here we show that wide-field illumination in the second near-infrared …

Dual Behavior Regulation: Tether‐Free Deep‐Brain Stimulation by Photothermal and Upconversion Hybrid Nanoparticles

F Sun, H Shen, Q Yang, Z Yuan, Y Chen… - Advanced …, 2023 - Wiley Online Library
Optogenetics has been plagued by invasive brain implants and thermal effects during photo‐
modulation. Here, two upconversion hybrid nanoparticles modified with photothermal …

Neural modulation with photothermally active nanomaterials

Y Wang, R Garg, D Cohen-Karni… - Nature Reviews …, 2023 - nature.com
Modulating neural electrophysiology with high precision is essential for understanding
neural communication and for the diagnosis and treatment of neural disorders. Photothermal …

Semiconducting polymer nanobioconjugates for targeted photothermal activation of neurons

Y Lyu, C Xie, SA Chechetka, E Miyako… - Journal of the American …, 2016 - ACS Publications
Optogenetics provides powerful means for precise control of neuronal activity; however, the
requirement of transgenesis and the incapability to extend the neuron excitation window into …

Thermogenetic neurostimulation with single-cell resolution

YG Ermakova, AA Lanin, IV Fedotov… - Nature …, 2017 - nature.com
Thermogenetics is a promising innovative neurostimulation technique, which enables robust
activation of neurons using thermosensitive transient receptor potential (TRP) cation …

Remote modulation of neural activities via near-infrared triggered release of biomolecules

W Li, R Luo, X Lin, AD Jadhav, Z Zhang, L Yan… - Biomaterials, 2015 - Elsevier
The capability to remotely control the release of biomolecules provides an unique
opportunity to monitor and regulate neural signaling, which spans extraordinary spatial and …

Optogenetics and thermogenetics: technologies for controlling the activity of targeted cells within intact neural circuits

JG Bernstein, PA Garrity, ES Boyden - Current opinion in neurobiology, 2012 - Elsevier
In recent years, interest has grown in the ability to manipulate, in a temporally precise
fashion, the electrical activity of specific neurons embedded within densely wired brain …

Photothermal inhibition of neural activity with near-infrared-sensitive nanotransducers

S Yoo, S Hong, Y Choi, JH Park, Y Nam - ACS nano, 2014 - ACS Publications
A neural stimulation technique that can inhibit neural activity reversibly and directly without
genetic modification is valuable for understating complex brain functions and treating brain …

Single-cell photothermal neuromodulation for functional mapping of neural networks

S Yoo, JH Park, Y Nam - ACS nano, 2018 - ACS Publications
Photothermal neuromodulation is one of the emerging technologies being developed for
neuroscience studies because it can provide minimally invasive control of neural activity in …

Tetherless near-infrared control of brain activity in behaving animals using fully implantable upconversion microdevices

Y Wang, X Lin, X Chen, X Chen, Z Xu, W Zhang, Q Liao… - Biomaterials, 2017 - Elsevier
Many nanomaterials can be used as sensors or transducers in biomedical research and
they form the essential components of transformative novel biotechnologies. In this study, we …