Angiogenesis is considered an important issue in the development of biomaterials for the
successful regeneration of tissues including bone. While growth factors are commonly used …

Angiogenesis is critical for bone tissue engineering. Stimulating proangiogenesis in an
engineered bone construct using bioglass or bioceramic is now attracting much attention …

Promoting angiogenesis is a key strategy for stimulating the repair of damaged tissues,
including bone. Among other proangiogenic factors, ions have recently been considered a …

The capacity to induce rapid vascular ingrowth during new bone formation is an important
feature of biomaterials that are to be used for bone regeneration. Akermanite, a Ca-, Mg-and …

Silicon (Si) is a trace element, which plays an important role in human bone growth. Si has
been incorporated into biomaterials for bone regeneration in order to improve their …

The regeneration capacity of the osteoporotic bones is generally lower than that of the
normal bones. Current methods of bone defect treatment for osteoporosis are not always …

In bone regeneration, silicon-based calcium phosphate glasses (Bioglasses) have been
widely used since the 1970s. However, they dissolve very slowly because of their high …

Aseptic loosening of a permanent prosthesis remains one of the most common reasons for
bone implant failure. To improve the fixation between implant and bone tissue as well as …

The facts that biomaterials affect the behavior of single type of cells have been widely
accepted. However, the effects of biomaterials on cell–cell interactions have rarely been …

Copper (Cu) has been reported to be able to stimulate vascularization/angiogenesis, which
is critical for regeneration of vascularized tissue in tissue engineering. Silicate bioceramics …