Lipid phenotypes and DNA methylation: a review of the literature
Abstract Purpose of Review Epigenetic modifications via DNA methylation have previously
been linked to blood lipid levels, dyslipidemias, and atherosclerosis. The purpose of this …
been linked to blood lipid levels, dyslipidemias, and atherosclerosis. The purpose of this …
The role of DNA methylation in dyslipidaemia: a systematic review
KVE Braun, T Voortman, K Dhana, J Troup… - Progress in Lipid …, 2016 - Elsevier
Epigenetic mechanisms, including DNA methylation and histone modifications, might be
involved in the regulation of blood lipid concentration variability and may thereby affect …
involved in the regulation of blood lipid concentration variability and may thereby affect …
Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study
S Sayols-Baixeras, I Subirana… - Human molecular …, 2016 - academic.oup.com
Lipid traits (total, low-density and high-density lipoprotein cholesterol, and triglycerides) are
risk factors for cardiovascular disease. DNA methylation is not only an inherited but also …
risk factors for cardiovascular disease. DNA methylation is not only an inherited but also …
DNA methylation in human lipid metabolism and related diseases
K Mittelstraß, M Waldenberger - Current opinion in lipidology, 2018 - journals.lww.com
The current review provides a literature overview of epigenetic modifications in lipid
metabolism and other lipid-related phenotypes and diseases focusing on EWAS of DNA …
metabolism and other lipid-related phenotypes and diseases focusing on EWAS of DNA …
[HTML][HTML] Role of genetic and environmental factors in DNA methylation of lipid metabolism
Z He, R Zhang, F Jiang, W Hou, C Hu - Genes & diseases, 2018 - Elsevier
A number of recent studies revealed that DNA methylation plays a central role in the
regulation of lipid metabolism. DNA methylation modifications are important regulators of …
regulation of lipid metabolism. DNA methylation modifications are important regulators of …
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids
Here we examine the association between DNA methylation in circulating leukocytes and
blood lipids in a multi-ethnic sample of 16,265 subjects. We identify 148, 35, and 4 novel …
blood lipids in a multi-ethnic sample of 16,265 subjects. We identify 148, 35, and 4 novel …
Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study
Background DNA methylation is a key epigenetic mechanism that is suggested to be
associated with blood lipid levels. We aimed to identify CpG sites at which DNA methylation …
associated with blood lipid levels. We aimed to identify CpG sites at which DNA methylation …
Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association …
Background—Genome-wide association studies have identified loci influencing circulating
lipid concentrations in humans; further information on novel contributing genes, pathways …
lipid concentrations in humans; further information on novel contributing genes, pathways …
[HTML][HTML] Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 …
Background: DNA methylation is influenced by diet and single nucleotide polymorphisms
(SNPs), and methylation modulates gene expression. Objective: We aimed to explore …
(SNPs), and methylation modulates gene expression. Objective: We aimed to explore …
DNA methylation of lipid-related genes affects blood lipid levels
L Pfeiffer, S Wahl, LC Pilling, E Reischl… - Circulation …, 2015 - Am Heart Assoc
Background—Epigenetic mechanisms might be involved in the regulation of interindividual
lipid level variability and thus may contribute to the cardiovascular risk profile. The aim of this …
lipid level variability and thus may contribute to the cardiovascular risk profile. The aim of this …