Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells
S Li, X Cong, H Gao, X Lan, Z Li, W Wang… - Journal of Experimental …, 2019 - Springer
Purpose Epithelial to mesenchymal transition (EMT) can contribute to gastric cancer (GC)
progression and recurrence following therapy. Tumor-associated neutrophils (TANs) are …
progression and recurrence following therapy. Tumor-associated neutrophils (TANs) are …
Interleukin-17–producing neutrophils link inflammatory stimuli to disease progression by promoting angiogenesis in gastric cancer
Purpose: Elevated levels of neutrophils have been associated with poor survival in various
cancers, but direct evidence supporting a role for neutrophils in the immunopathogenesis of …
cancers, but direct evidence supporting a role for neutrophils in the immunopathogenesis of …
Tumor-infiltrating CD4+ Th17 cells produce IL-17 in tumor microenvironment and promote tumor progression in human gastric cancer
T Iida, M Iwahashi, M Katsuda, K Ishida… - Oncology …, 2011 - spandidos-publications.com
Recently, a subset of IL-17 producing T cells distinct from Th1 or Th2 cells has been
described as key players in inflammation and autoimmune diseases as well as cancer …
described as key players in inflammation and autoimmune diseases as well as cancer …
IL-17 promotes tumor angiogenesis through Stat3 pathway mediated upregulation of VEGF in gastric cancer
X Wu, T Yang, X Liu, JN Guo, T Xie, Y Ding, M Lin… - Tumor Biology, 2016 - Springer
Gastric cancer is the world's second most common malignancy and is a major threat to
global health. IL-17, a CD4 T cell-derived mediator of angiogenesis, plays a major role in …
global health. IL-17, a CD4 T cell-derived mediator of angiogenesis, plays a major role in …
Interaction with neutrophils promotes gastric cancer cell migration and invasion by inducing epithelial-mesenchymal transition
W Zhang, J Gu, J Chen, P Zhang, R Ji… - Oncology …, 2017 - spandidos-publications.com
Emerging evidence has revealed that neutrophils have phenotypic and functional plasticity.
Neutrophils could be polarized towards a pro-tumor phenotype by tumor-derived factors. In …
Neutrophils could be polarized towards a pro-tumor phenotype by tumor-derived factors. In …
[HTML][HTML] Cancer-associated fibroblasts promote the migration and invasion of gastric cancer cells via activating IL-17a/JAK2/STAT3 signaling
J Zhang, S Li, Y Zhao, P Ma, Y Cao, C Liu… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Cancer-associated fibroblasts (CAFs), as the activated stroma cells, contribute
to tumor progression via the release of cytokines, growth factors, and hormones. However …
to tumor progression via the release of cytokines, growth factors, and hormones. However …
[HTML][HTML] Intratumoral IL17-producing cells infiltration correlate with antitumor immune contexture and improved response to adjuvant chemotherapy in gastric cancer
JT Wang, H Li, H Zhang, YF Chen, YF Cao, RC Li… - Annals of …, 2019 - Elsevier
Abstract Background Tumor IL17-producing (IL17A+) cells infiltration has different
prognostic values among various cancers. The objective of this study was to assess the …
prognostic values among various cancers. The objective of this study was to assess the …
The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms
YX Jiang, SW Yang, PA Li, X Luo, ZY Li, YX Hao… - Oncogene, 2017 - nature.com
Postoperative recurrence and metastasis have crucial roles in the poor prognosis of gastric
cancer patients. Previous studies have indicated that gastric cancer originates from cancer …
cancer patients. Previous studies have indicated that gastric cancer originates from cancer …
CD8+ T cells that produce interleukin-17 regulate myeloid-derived suppressor cells and are associated with survival time of patients with gastric cancer
BACKGROUND & AIMS: CD8+ T cells that produce interleukin (IL)-17 (Tc17 cells) promote
inflammation and have been identified in tumors. We investigated their role in the …
inflammation and have been identified in tumors. We investigated their role in the …
IL‑10 secreted by cancer‑associated macrophages regulates proliferation and invasion in gastric cancer cells via c‑Met/STAT3 signaling
L Chen, Y Shi, X Zhu, W Guo, M Zhang… - Oncology …, 2019 - spandidos-publications.com
Gastric cancer is one of the most common types of human cancer, and it is additionally one
of the leading causes of cancer‑associated mortality worldwide. Previous studies have …
of the leading causes of cancer‑associated mortality worldwide. Previous studies have …
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