Iron-Rich Conditions Induce OmpA and Virulence Changes of Acinetobacter baumannii

H Liu, C Cao, F Qiu, HN Huang, H Xie, R Dong… - Frontiers in …, 2021 - frontiersin.org
Background: Iron ions affect the expression of outer membrane protein A (OmpA), a major
pathogenic protein in Acinetobacter baumannii. Objective: To analyze the effect of iron ions …

Pneumonia infection in mice reveals the involvement of the feoA gene in the pathogenesis of Acinetobacter baumannii

L Álvarez-Fraga, JC Vázquez-Ucha… - Virulence, 2018 - Taylor & Francis
Acinetobacter baumannii has emerged in the last decade as an important nosocomial
pathogen. To identify genes involved in the course of a pneumonia infection, gene …

A comprehensive study of the relationship between the production of β‐lactamase enzymes and iron/siderophore uptake regulatory genes in clinical isolates of …

M Porbaran, H Tahmasebi… - International Journal of …, 2021 - Wiley Online Library
Background. The iron/siderophore uptake system (IUS) involved in the Acinetobacter
baumannii pathogenicity. However, IUS's role in antibiotic resistance and the production of β …

Investigation of the human pathogen Acinetobacter baumannii under iron limiting conditions

BA Eijkelkamp, KA Hassan, IT Paulsen, MH Brown - BMC genomics, 2011 - Springer
Background Iron acquisition systems are important virulence factors in pathogenic bacteria.
To identify these systems in Acinetobacter baumannii, the transcriptomic response of the …

Global Transcriptomic Analysis During Murine Pneumonia Infection Reveals New Virulence Factors in Acinetobacter baumannii

M Martínez-Guitián, JC Vázquez-Ucha… - The Journal of …, 2021 - academic.oup.com
Background Infections caused by multidrug-resistant pathogens such as Acinetobacter
baumannii constitute a major health problem worldwide. In this study we present a global in …

[HTML][HTML] The role of quorum sensing, biofilm formation, and iron acquisition as key virulence mechanisms in Acinetobacter baumannii and the corresponding anti …

SKK Law, HS Tan - Microbiological Research, 2022 - Elsevier
Acinetobacter baumannii is a nosocomial pathogen responsible for several serious
infections, including pneumonia, sepsis, and meningitis. The propensity of this bacterium to …

Current approaches to explain the virulence of Acinetobacter baumannii

G Aşık - Mikrobiyoloji bulteni, 2011 - europepmc.org
Acinetobacter baumannii which is one of the most frequent nosocomial pathogens, has
drawn attention in the last years owing to multi-drug resistant strains. A. baumannii may give …

Investigation of the Virulence Factors and Molecular Characterization of the Clonal Relations of Multidrug-Resistant Acinetobacter baumannii Isolates

HM Ali, MZM Salem, MS El-Shikh… - Journal of AOAC …, 2017 - academic.oup.com
Multidrug-resistant (MDR) Acinetobacter baumannii infections are a great public health
concern and demand continuous surveillance and antibiotic stewardship. Virulence traits …

Iron limitation enhances acyl homoserine lactone (AHL) production and biofilm formation in clinical isolates of Acinetobacter baumannii

F Modarresi, O Azizi, MR Shakibaie, M Motamedifar… - Virulence, 2015 - Taylor & Francis
Acinetobacter baumannii is an important source of infections in intensive care units (ICUs) of
our hospitals in Kerman, Iran and the most frequently isolated strains produce biofilm. There …

Monoclonal antibodies against the iron regulated outer membrane Proteins of Acinetobacter baumannii are bactericidal

VK Goel, A Kapil - BMC microbiology, 2001 - Springer
Background Iron is an important nutrient required by all forms of life. In the case of human
hosts, the free iron availability is 10-18 M, which is far less than what is needed for the …