Alpha-Fetoprotein Binds Toxins and Can Be Used to Treat Cancer

VN Pak - Medical Research Archives, 2022 - esmed.org
The inefficiency of the immune system to kill cancer cells leads to the disease. Like in
pregnancy, oncofetal proteins counteract the immune attack. Alpha-fetoprotein is an …

Alpha-Fetoprotein: A Revolutionary Anti-Cancer Drug

VN Pak - Medical Research Archives, 2023 - esmed.org
Alpha-fetoprotein is an oncofetal protein the embryo produces during fetal development. The
protein serves two critical functions simultaneously: it delivers nutrients to growing embryo …

α-fetoprotein-binding toxins and teratogens against cancer

VN Pak - Therapeutic Delivery, 2019 - Taylor & Francis
Conclusion Recombinant human AFP is close to becoming a registered drug [17]. Then it
could be provided to patients together with registered drugs-teratogens and AFP-binding …

[图书][B] Alpha-fetoprotein and Its Receptor in Fixing the Cancer Brakes

VN Pak - 2021 - books.google.com
This book examines the crucial role of a unique alpha-fetoprotein (AFP) in the treatment of
cancer. AFP can deliver toxins through specific receptors re-expressed in the majority of …

The use of alpha-fetoprotein for the treatment of autoimmune diseases and cancer

VN Pak - Therapeutic delivery, 2018 - Taylor & Francis
Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated
endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha …

Detection of membrane-bound α-fetoprotein in human hepatoma cell lines by monoclonal antibody 19F12

S Hosokawa, M Muramatsu, K Nagaike - Cancer research, 1989 - AACR
Monoclonal antibodies against human α-fetoprotein (AFP) were obtained by the hybridoma
technique and studied with regard to their reactivities with the human hepatoma cell lines …

Species cross-reaction of alpha-fetoproteins and break-down of the tolerance to alpha-fetoprotein by immunization with heterologous alpha-fetoprotein

S Nishi, H Watabe, H Hirai - Tumor research, 1973 - pubmed.ncbi.nlm.nih.gov
PIP: Immunological character of alpha fetoprotein (AFP) was investigated in respect to
immunological relationship of human and animal AFP; responses to the injection of …

Biological role of α-fetoprotein in cancer: prospects for anticancer therapy

GJ Mizejewski - Expert review of anticancer therapy, 2002 - Taylor & Francis
α-fetoprotein has long been considered the 'gold-standard 'in the field of tumor markers.
During the several decades since the recognition of mammalian α-fetoprotein as a tumor …

α-fetoprotein: Studies of tumor-associated antigen cytotoxicity in mouse hepatoma BW7756

GJ Mizejewski, RP Allen - Clinical Immunology and Immunopathology, 1978 - Elsevier
Mouse hepatoma BW7756, a primary hepatocellular carcinoma of spontaneous origin, has
been presently employed as a tumor cell model for the in vitro study of tumor-associated …

High anti-tumor activity of a novel alpha-fetoprotein-maytansinoid conjugate targeting alpha-fetoprotein receptors in colorectal cancer xenograft model

P Griffin, WA Hill, F Rossi, R Boohaker, K Stinson… - Cancer Cell …, 2023 - Springer
The alpha-fetoprotein receptor (AFPR) is a novel target for cancer therapeutics. It is
expressed on most cancers and myeloid derived suppressor cells (MDSCs) but generally …