Nonalcoholic steatohepatitis (NASH) causes liver extracellular matrix (ECM) remodeling and
is a risk factor for fibrosis and hepatocellular carcinoma (HCC). Microcystin-LR (MCLR) is a …

Microcystin-LR (MCLR) is a hepatotoxic cyanotoxin reported to cause a phenotype similar to
nonalcoholic steatohepatitis (NASH). NASH is a common progressive liver disease that …

Abstract Microcystin-LR (MCLR), a cyanotoxin widely present in freshwater, has been shown
to have potent acute hepatotoxicity. However, the chronic toxicity of low-dose MCLR remains …

Microcystins (MCs) produced by cyanobacteria pose serious threats to human health.
However, the contribution of long-term exposure to MCs to the development of nonalcoholic …

Microcystins are potent hepatotoxins that have become a global health concern in recent
years. Their actions in at-risk populations with pre-existing liver disease is unknown. We …

Microcystin-LR (MCLR) is a cyanotoxin produced by blue-green algae that causes liver and
kidney toxicities. MCLR toxicity is dependent on cellular uptake through the organic anion …

We have previously shown in a murine model of Non-alcoholic Fatty Liver Disease (NAFLD)
that chronic, low-dose exposure to the Harmful Algal Bloom cyanotoxin microcystin-LR (MC …

Background. Acute exposure to high concentrations of microcystin-LR (MC-LR) can cause
significant hepatocyte injury. Aim. To document the effects of long-term, low-dose MC-LR …

Microcystin-leucine arginine (MC-LR) is a potent liver toxin produced by freshwater
cyanobacteria, also known as blue-green algae. While harmful algal blooms are increasing …

Microcystin-LR (MCLR) is a liver and kidney toxin produced by cyanobacteria. Recently, it
was demonstrated that MCLR exposure drives the progression of high fat/high cholesterol …