Nontemplated nucleotide additions distinguish the small RNA composition in cells from exosomes
Functional biomolecules, including small noncoding RNAs (ncRNAs), are released and
transmitted between mammalian cells via extracellular vesicles (EVs), including endosome …
transmitted between mammalian cells via extracellular vesicles (EVs), including endosome …
Characterization of human plasma-derived exosomal RNAs by deep sequencing
Background Exosomes, endosome-derived membrane microvesicles, contain specific RNA
transcripts that are thought to be involved in cell-cell communication. These RNA transcripts …
transcripts that are thought to be involved in cell-cell communication. These RNA transcripts …
Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome
Extracellular vesicles (EVs) mediate cell-to-cell communication by delivering or displaying
macromolecules to their recipient cells. While certain broad-spectrum EV effects reflect their …
macromolecules to their recipient cells. While certain broad-spectrum EV effects reflect their …
[HTML][HTML] Comparing small urinary extracellular vesicle purification methods with a view to RNA sequencing—Enabling robust and non-invasive biomarker research
Small extracellular vesicles (EVs) are 50–200 nm sized mediators in intercellular
communication that reflect both physiological and pathophysiological changes of their …
communication that reflect both physiological and pathophysiological changes of their …
[HTML][HTML] Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine
Micro RNAs (miRNAs) have been shown to circulate in biological fluids and are enclosed in
vesicles such as exosomes; they are present in urine and represent a noninvasive …
vesicles such as exosomes; they are present in urine and represent a noninvasive …
Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and …
BWM Van Balkom, AS Eisele, DM Pegtel… - Journal of …, 2015 - Taylor & Francis
Exosomes are small vesicles that mediate cell–cell communication. They contain proteins,
lipids and RNA, and evidence is accumulating that these molecules are specifically sorted …
lipids and RNA, and evidence is accumulating that these molecules are specifically sorted …
Characterization and selective incorporation of small non-coding RNAs in non-small cell lung cancer extracellular vesicles
C Li, F Qin, F Hu, H Xu, G Sun, G Han, T Wang, M Guo - Cell & bioscience, 2018 - Springer
Abstract Background Extracellular vesicles (EVs) play important roles in intercellular
communication through the delivery of their cargoes, which include proteins, lipids, and …
communication through the delivery of their cargoes, which include proteins, lipids, and …
EVmiRNA: a database of miRNA profiling in extracellular vesicles
Extracellular vesicles (EVs), such as exosomes and microvesicles, acted as cell-to-cell
communication vectors and potential biomarkers for diseases. microRNAs (miRNAs) are the …
communication vectors and potential biomarkers for diseases. microRNAs (miRNAs) are the …
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood
L Cheng, RA Sharples, BJ Scicluna… - Journal of extracellular …, 2014 - Taylor & Francis
Introduction microRNA (miRNA) are small non-coding RNA species that are transcriptionally
processed in the host cell and released extracellularly into the bloodstream. Normally …
processed in the host cell and released extracellularly into the bloodstream. Normally …
RNA in extracellular vesicles
Cells release a range of membrane‐enclosed extracellular vesicles (EVs) into the
environment. Among them, exosomes and microvesicles (collectively measuring 40–1000 …
environment. Among them, exosomes and microvesicles (collectively measuring 40–1000 …