Esophageal cancer (EC) causes hundreds of thousands of deaths a year worldwide,
especially the major subtype esophageal squamous cell carcinoma (ESCC). With the advent …

Cancer is a disease of genome instability and genomic alterations; now, genomic
heterogeneity is rapidly emerging as a defining feature of cancer, both within and between …

Esophageal cancer is among the most common tumors in the world and is associated with
poor outcomes, with a 5-year survival rate of about 10–20%. Two main histological subtypes …

Esophageal squamous cell carcinoma (ESCC) is a common malignancy without effective
therapy. The exomes of more than 600 ESCCs have been sequenced in the past 4 years …

Esophageal squamous cell carcinoma (ESCC) has a high mortality rate. To determine the
molecular basis of ESCC development, this study sought to identify characteristic genome …

The morbidity and mortality of esophageal squamous cell carcinoma (ESCC) remains high
in China. ESCC is significantly influenced by a complex interplay of environmental and …

Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors
with poor prognosis worldwide. The poor prognosis is due to the advanced stage at the time …

Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer
death worldwide and is characterized by numerous genetic mutations. TNM staging is not …

Background: Esophageal squamous cell carcinoma (ESCC) is associated with poor
prognosis and occurs with high frequency in China. The germline mutation profile in ESCC …

Background E sophageal squamous cell carcinoma (ESCC) is highly prevalent in China and
other Asian countries, as a major cause of cancer-related mortality. ESCC displays complex …