Resistance to thyroid hormone (RTH) is a clinical syndrome defined by impaired sensitivity
to thyroid hormone (TH) and its more common form is caused by mutations in the thyroid …

Resistance to thyroid hormone beta (RTHβ) is a syndrome characterized by reduced
responsiveness of peripheral tissues to thyroid hormone (TH). Affected individuals have …

Background: Thyroid hormone (TH) acts via nuclear thyroid hormone receptors (TRs). TR
isoforms (TRα1, TRα2, TRβ1, TRβ2) are encoded by distinct genes (THRA and THRB) and …

Thyroid hormone (TH) action is crucial for the development of several tissues. A number of
syndromes are associated with reduced responsiveness to thyroid hormones, expanding the …

Resistance to thyroid hormone syndrome (RTH) is an autosomal dominant or recessive
genetic disease caused by mutation of either the thyroid hormone receptorβ (THR-β) gene …

Resistance to thyroid hormone (RTH) is an inherited syndrome characterized by reduced
tissue responsiveness to thyroid hormone. Subjects have elevated serum thyroid hormone …

There are two genes that express the major thyroid hormone receptor isoforms. Mutations in
both these genes have given rise to Resistance to Thyroid Hormone (RTH) syndromes …

Context: The most common cause of resistance to thyroid hormone (RTH) is heterozygous
thyroid hormone receptor β (THRB) gene mutations. Homozygous mutations in the THRB …

Resistance to thyroid hormone (RTH) action is due to mutations in theβ-isoform of the thyroid
hormone receptor (TR-β). RTH patients display inappropriate central secretion of TRH from …

Background The syndrome of resistance to thyroid hormone (RTH) is caused by mutations in
the thyroid hormone receptor β gene (THRB). The syndrome varies from asymptomatic to …