Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is a major factor in the
pathogenesis of dry age-related macular degeneration (AMD). Although the therapeutic …

Retinal detachment (RD) induces ischemia and oxygen deficiency in the retina and results
in multiple pathological events; photoreceptor cell degeneration and death is the eventual …

Over the past decade, the field of mesenchymal stem cell (MSC) therapy has exhibited rapid
growth. Due to their regenerative, reparatory, and immunomodulatory capacities, MSCs …

Purpose: Human corneal endothelial cells (hCECs) have been considered unable to
regenerate in vivo, resulting in corneal decompensation after significant loss of hCECs …

Retinal pigment epithelial (RPE) cellular senescence is regarded as an initiator for age-
related macular degeneration (AMD). We previously demonstrated that by the coculture way …

Traumatic optic neuropathy results in the loss of retinal ganglion cells (RGCs), leading to
unavoidable visual impairment. However, there is no effective therapy by far. Accumulated …

Mesenchymal stem cells (MSCs) were, due to their immunomodulatory and pro-angiogenic
characteristics, extensively explored as new therapeutic agents in cell-based therapy of …

Purpose This study was aimed at exploring the function of Exosomes isolated from bone
marrow-derived mesenchymal stem cells (BMSC-Exos) in corneal wound healing and at …

Corneal injury (CI) affects corneal integrity and transparency, deteriorating the patient's
quality of life. This study aimed to explore the molecular mechanisms by which exosomes …

BACKGROUND: Retinal degenerative disease (RDD), one of the most common causes of
blindness, is predominantly caused by the gradual death of retinal pigment epithelial cells …