Laboratory model organisms have provided a window into how the immune system
functions. An increasing body of evidence, however, suggests that the immune responses of …

Trichuris trichiura is a highly prevalent intestinal helminth of humans with a well‐
characterized animal model, Trichuris muris in the mouse. Relating the murine work back to …

Trichuris muris is a mouse intestinal parasitic nematode that inhabits the large intestine of its
host and induces a strong immune response. The effects of this strong anti-parasite …

Infection with soil-transmitted helminths (STH) remains a major burden on global health and
agriculture. Our understanding of the immunological mechanisms that govern whether an …

Infections with high doses of intestinal nematodes result in protective immunity based on
robust type 2 responses in most mouse lines under laboratory conditions. Here, we report on …

Helminth parasites are a large group of multicellular organisms that affect vast numbers of
humans and are a major cause of disease. Several relevant experimental murine models …

The majority of experiments investigating the immune response to gastrointestinal helminth
infection use a single bolus infection. However, in situ individuals are repeatedly infected …

The J and S isolates of Trichuris muris have different infection profiles in C57BL/6 mice; J
worms are expelled, S worms survive to chronicity. Building on this, the ability of the J and S …

Intestinal nematode parasites are some of the most prevalent infections of man. Infections
tend to be chronic and, after drug treatment, have high reinfection rates. Control programs …

Trichuris muris is a natural pathogen of mice and is biologically and antigenically similar to
species of Trichuris that infect humans and livestock1. Infective eggs are given by oral …