Animal models of drug relapse and craving after voluntary abstinence: a review
Relapse to drug use during abstinence is a defining feature of addiction. During the last
several decades, this clinical scenario has been studied at the preclinical level using classic …
several decades, this clinical scenario has been studied at the preclinical level using classic …
Animal models of drug relapse and craving: from drug priming-induced reinstatement to incubation of craving after voluntary abstinence
High rates of relapse to drug use during abstinence is a defining feature of drug addiction. In
abstinent drug users, drug relapse is often precipitated by acute exposure to the self …
abstinent drug users, drug relapse is often precipitated by acute exposure to the self …
Forced abstinence model of relapse to study pharmacological treatments of substance use disorder
CM Reichel, RA Bevins - Current drug abuse reviews, 2009 - ingentaconnect.com
Understanding and preventing relapse to drug use is one of the most difficult challenges
faced by clinicians and practitioners in the struggle to help people remain abstinent. In this …
faced by clinicians and practitioners in the struggle to help people remain abstinent. In this …
Recent developments in animal models of drug relapse
Drug craving and relapse to drug use during abstinence are defining features of addiction.
Evidence indicates that drug craving and relapse in humans are often provoked by acute …
Evidence indicates that drug craving and relapse in humans are often provoked by acute …
Relapse to opioid seeking in rat models: behavior, pharmacology and circuits
DJ Reiner, I Fredriksson, OM Lofaro… - …, 2019 - nature.com
Lifetime relapse rates remain a major obstacle in addressing the current opioid crisis.
Relapse to opioid use can be modeled in rodent studies where drug self-administration is …
Relapse to opioid use can be modeled in rodent studies where drug self-administration is …
Relapse to drug seeking following prolonged abstinence: the role of environmental stimuli
RA Fuchs, HC Lasseter, DR Ramirez, X Xie - Drug Discovery Today …, 2008 - Elsevier
Successful treatment of drug addiction must involve relapse prevention informed by our
understanding of the neurobiological bases of drug relapse. In humans, exposure to drug …
understanding of the neurobiological bases of drug relapse. In humans, exposure to drug …
[HTML][HTML] Context-induced relapse after extinction versus punishment: similarities and differences
Results from clinical studies suggest that drug relapse and craving are often provoked by
exposure to drug-associated contexts. Since 2002, this phenomenon has been modeled in …
exposure to drug-associated contexts. Since 2002, this phenomenon has been modeled in …
The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research
Background and rationale Results from many clinical studies suggest that drug relapse and
craving are often provoked by acute exposure to the self-administered drug or related drugs …
craving are often provoked by acute exposure to the self-administered drug or related drugs …
The reinstatement model of drug relapse: history, methodology and major findings
Rational and objectives. The reinstatement model is currently used in many laboratories to
investigate mechanisms underlying relapse to drug seeking. Here, we review briefly the …
investigate mechanisms underlying relapse to drug seeking. Here, we review briefly the …
Neurobiology of relapse to heroin and cocaine seeking: a review
The objective of this article is to review data from studies that used a reinstatement model in
rats to elucidate the neural mechanisms underlying relapse to heroin and cocaine seeking …
rats to elucidate the neural mechanisms underlying relapse to heroin and cocaine seeking …