[HTML][HTML] Disulfiram-loaded niosomes reduces cancerous phenotypes in oral squamous cell carcinoma cells

MZ Motlagh, N Mahdavi, Z Miri-Lavasani… - Cell Journal …, 2023 - ncbi.nlm.nih.gov
Objective: Surgery and chemotherapy are the most common therapeutic strategies proposed
for oral squamous cell carcinoma (OSCC). However, some of the disadvantages associated …

Development, characterization and efficacy of niosomal diallyl disulfide in treatment of disseminated murine candidiasis

M Alam, S Zubair, M Farazuddin, E Ahmad… - … , Biology and Medicine, 2013 - Elsevier
In the current study, a novel niosome based formulation of diallyl disulfide (DADS) was
evaluated for its potential to treat disseminated candidiasis in mouse model. Among various …

Preparation of disulfiram naonosuspensions and their anti-tumor efficacy in vitro and in vivo

Y JI, B LIU, R YU, X WANG - Acta Pharmaceutica Sinica, 2019 - pesquisa.bvsalud.org
Disulfiram (DSF) is a traditional anti-alcohol drug, but it was recently found that DSF has
strong inhibitory effect on the growth of a variety of cancer cells. However, its clinical …

Hybrid of niosomes and bio-synthesized selenium nanoparticles as a novel approach in drug delivery for cancer treatment

M Gharbavi, B Johari, N Mousazadeh, B Rahimi… - Molecular Biology …, 2020 - Springer
The current study intends to investigate a novel drug delivery system (DDS) based on
niosomes structure (NISM) and bovine serum albumin (BSA) which was formulated to BSA …

Stable loading and delivery of disulfiram with mPEG-PLGA/PCL mixed nanoparticles for tumor therapy

W Song, Z Tang, T Lei, X Wen, G Wang… - … , Biology and Medicine, 2016 - Elsevier
Disulfiram (DSF) showed great potential in an in vitro tumor therapy study; however, those
results could not be applied to an in vivo study due to the extreme instability of DSF in blood …

Recent advances in the delivery of disulfiram: a critical analysis of promising approaches to improve its pharmacokinetic profile and anticancer efficacy

MA Farooq, M Aquib, DH Khan, Z Hussain… - DARU Journal of …, 2019 - Springer
Background Disulfiram (DSF) has a long history of being used as a first-line promising
therapy for treatment of alcoholism in human. Besides its prominence in the treatment of …

Soybean lecithin stabilizes disulfiram nanosuspensions with a high drug-loading content: remarkably improved antitumor efficacy

H Li, B Liu, H Ao, J Fu, Y Wang, Y Feng, Y Guo… - Journal of …, 2020 - Springer
Disulfiram (DSF) has been considered as “Repurposing drug” in cancer therapy in recent
years based on its good antitumor efficacy. DSF is traditionally used as an oral drug in the …

Anti-cancer effects of disulfiram in head and neck squamous cell carcinoma via autophagic cell death

YM Park, YY Go, SH Shin, JG Cho, JS Woo, JJ Song - PLoS One, 2018 - journals.plos.org
Background Disulfiram (DSF), which is used to treat alcohol dependence, has been reported
to have anti-cancer effects in various malignant tumors. In this study, we investigated the anti …

[HTML][HTML] Functionalized niosomes as a smart delivery device in cancer and fungal infection

P Aparajay, A Dev - European journal of pharmaceutical sciences, 2022 - Elsevier
Various diseases remain untreated due to lack of suitable therapeutic moiety or a suitable
drug delivery device, especially where toxicities and side effects are the primary reason for …

Nanoparticles as drug delivery systems in the treatment of oral squamous cell carcinoma: current status and recent progression

S Cui, H Liu, G Cui - Frontiers in Pharmacology, 2023 - frontiersin.org
Oral squamous cell carcinoma (OSCC) is a common human malignancy with an estimated
incidence of around 377,713 new cases worldwide in 2020. Despite the advance in clinical …