Despite abundant research in the field of antifungal drug discovery, fungal infections remain
a significant healthcare burden. There is an emerging need for the development of novel …

Fungi are one of the most neglected pathogens apparent from the fact that the Amphotericin
B, a polyene antibiotic, discovered way back in 1956 is still used as a'gold standard'for …

In the recent past, prevalence of life threatening fungal diseases have increased rapidly in
immune-compromised cases such as acquired immunodeficiency syndrome (AIDS), cancer …

Fungal infections have aroused much interest over the last years because of their
involvement in several human diseases. Immunocompromission due to transplant-related …

Increasing incidence of fungal infections of recent times requires immediate intervention.
Fungal infections are seldom construed at initial stages that intensify the severity of …

The emergence of new fungal pathogens makes the development of new antifungal drugs a
medical imperative that in recent years motivates the talents of numerous investigators …

With the increasing morbidity and mortality of invasive fungal infections and the emergence
of severe antifungal drug resistance, new drug targets and novel antifungal agents are …

The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Highlights•Natural products play a crucial role in antifungal drug discovery.•Natural products
represent many first-in-class antifungal agents in clinical trials with new modes of …

Promising new compounds have recently been identified in an effort to supplement the
relatively sparse portfolio of antifungal drugs. Many of these compounds have defined …