Mammalian models are frequently used for preclinical evaluation of new drug delivery
systems (DDS). However, valid mammalian models are expensive, time-consuming, and not …

The chick embryo chorioallantoic membrane (CAM) is a preclinical model widely used for
vascular and anti-vascular effects of therapeutic agents in vivo. In this study, we examine the …

Simple Summary The chorioallantoic membrane of an avian embryo is a simple, low-cost,
low-maintenance, and well-available in vivo animal model with many advantages in the field …

The advance of perinatal medicine has improved the survival of extremely premature
babies, thereby creating a new and heterogeneous patient group with limited information on …

During avian development the mesodermal layers of the allantois and chorion fuse to form
the chorioallantoic membrane (CAM). This structure rapidly expands generating a rich …

Fertilized chicken eggs are employed as an alternative to mammalian models. The
chorioallantoic membrane (CAM) of the chick embryo is widely used for examination of …

During avian development the mesodermal layers of the allantois and chorion fuse to form
the chorioallantoic membrane (CAM). This structure rapidly expands generating a rich …

The discovery and development of any given drug is invariably a lengthy and expensive
process in the pharmaceutical industry. It starts with the identification and validation of the …

The development of new biomaterials and drug delivery systems necessitates animal
experimentation to demonstrate biocompatibility and therapeutic efficacy. Reduction and …

Animal models play a crucial role in fundamental and medical research. Progress in the
fields of drug discovery, regenerative medicine and cancer research among others are …