Sepsis occurs in 14-37% of patients admitted to intensive care units and sepsis associated
encephalopathy (SAE) is its severe complication. In an attempt to provide insight into the …

The brain is one of the first organs affected during sepsis development resulting in apoptosis
for a short-term and cognitive impairment for a long-term. Despite its importance, the …

Sepsis and septic shock are the commonest causes of death in the intensive care units.
Although recent research have improved our understanding of the progress and …

Sepsis-associated encephalopathy is a common neurological complication of sepsis and is
responsible for higher mortality and poorer long-term outcomes in septic patients. Sepsis …

Background Septic encephalopathy is a severe brain dysfunction caused by systemic
inflammation in the absence of direct brain infection. Changes in cerebral blood flow …

The neuropathological correlates of encephalopathy and autonomic dysfuction in septic
shock are unclear. We performed post mortem analysis of 5 brain areas susceptible to …

Sepsis is an organ dysfunction caused by an uncontrolled inflammatory response from the
host to an infection. Sepsis is the main cause of morbidity and mortality in intensive care …

Brain dysfunction is frequently observed in sepsis as a consequence of changes in cerebral
structure and metabolism, resulting in worse outcome and reduced life-quality of surviving …

Objective: To investigate whether apoptosis is a possible mechanism of brain dysfunction
occurring in septic syndrome. Design: Experimental prospective study. Setting: Laboratory of …

Central nervous system (CNS) dysfunction secondary to sepsis is characterized by long‐
term cognitive impairment. It was observed that oxidative damage, energetic metabolism …