Type 2 immunity is characterized by the production of IL-4, IL-5, IL-9 and IL-13, and this
immune response is commonly observed in tissues during allergic inflammation or infection …

Type 2 immunity mediates protective responses to helminths and pathological responses to
allergens, but it also has broad roles in the maintenance of tissue integrity, including wound …

Type 2 helper T (Th2) cells, a subset of CD4+ T cells, play an important role in the host
defense against pathogens and allergens by producing Th2 cytokines, such as interleukin-4 …

Type 2 immune responses are defined by the cytokines interleukin-4 (IL-4), IL-5, IL-9 and IL-
13, which can either be host protective or have pathogenic activity. Type 2 immunity …

Fibrosis in response to tissue damage or persistent inflammation is a pathological hallmark
of many chronic degenerative diseases. By using a model of acute peritoneal inflammation …

Abstract Purpose of Review Macrophages are central players in the immune response
following tissue injury. These cells perform many functions, and the changing tissue …

Although tremendous progress has been achieved in understanding the molecular basis of
tissue repair and regeneration in diverse model organisms, the tendency of mammals for …

Inflammatory monocytes and tissue-resident macrophages are key regulators of tissue
repair, regeneration, and fibrosis. After tissue injury, monocytes and macrophages undergo …

Inflammation and fibrosis are two inter‐related conditions with many overlapping
mechanisms. Three specific cell types, macrophages, T helper cells, and myofibroblasts …

Inflammation is a response to infections or tissue injuries. Inflammation was once defined by
clinical signs, later by the presence of leukocytes, and nowadays by expression of …