A new method was developed for the estimation of polyethylenimine (PEI) to nucleic acid
ratio at which the polyplex was completely formed. The assay relied on the attraction of …

Chitosan (CS) combined with poly‐L‐arginine (PLA) was formulated and evaluated for its
performance to deliver siRNA to HeLa cells expressing enhanced green fluorescent protein …

We developed a novel small interfering RNA (siRNA) delivery system using a ternary
complex with polyethyleneimine (PEI) and γ-polyglutamic acid (γ-PGA), which showed …

This study is to prepare chitosan-based siRNA nano-carriers (Chi-TPP-siRNA) using ionic
gelation between cationic chitosan and anionic tripolyphosphate (TPP) for delivery of siRNA …

The aim of this study was to investigate chitosan/siRNA complexes formulated with various
chitosan salts (CS) including chitosan aspartate (CS-Asp), chitosan glutamate (CS-Glu) …

Biodegradable and biocompatible poly (d, l-lactic-co-glycolic acid)(PLGA) was conjugated to
the 5′-thiol end of signal transducer and activator of transcription 3 (STAT3) small …

The success of siRNA gene therapy requires the availability of safe and efficient delivery
systems. In the present study, we investigated poly (vinyl benzyl trimethylammonium …

Chitosan (CS) surface-modified poly (d, l-lactide-co-glycolide)(PLGA) nanospheres (NS) for
a siRNA delivery system were evaluated in vitro. siRNA-loaded PLGA NS were prepared by …

Currently, gene therapy is considered as a potentially universal approach to the treatment of
a wide range of diseases, such as cancer, cardiovascular diseases, diabetes, inherited …

To develop a small interfering RNA (siRNA) delivery system with low cytotoxicity and high
transfection efficiency, siRNA was conjugated to poly (ethylene glycol) via a disulfide linkage …