A Novel Antifungal Is Active against Candida albicans Biofilms and Inhibits Mutagenic Acetaldehyde Production In Vitro
MT Nieminen, L Novak-Frazer, V Rautemaa… - Plos one, 2014 - journals.plos.org
The ability of C. albicans to form biofilms is a major virulence factor and a challenge for
management. This is evident in biofilm-associated chronic oral-oesophageal candidosis …
management. This is evident in biofilm-associated chronic oral-oesophageal candidosis …
Hydroquinones including tetrachlorohydroquinone inhibit Candida albicans biofilm formation by repressing hyphae-related genes
Candida albicans is an opportunistic pathogenic fungus responsible for candidiasis. The
pathogen readily forms antifungal agent-resistant biofilms on implanted medical devices or …
pathogen readily forms antifungal agent-resistant biofilms on implanted medical devices or …
Alizarin and Chrysazin Inhibit Biofilm and Hyphal Formation by Candida albicans
Candida albicans is one of the most common pathogen causes fungal infections. This
opportunistic pathogen can form biofilms comprised of yeast, hyphae and pseudo hyphal …
opportunistic pathogen can form biofilms comprised of yeast, hyphae and pseudo hyphal …
Acetaldehyde inhibits the yeast-to-hypha conversion and biofilm formation in Candida albicans
NM Chauhan, JS Raut, SM Karuppayil - Mycoscience, 2011 - Springer
In Candida albicans, alcohol metabolism is implicated in biofilm formation. The alcohol
dehydrogenase gene (ADH1) is involved in the conversion of acetaldehyde to ethanol and …
dehydrogenase gene (ADH1) is involved in the conversion of acetaldehyde to ethanol and …
Screening of Pharmacologically Active Small Molecule Compounds Identifies Antifungal Agents Against Candida Biofilms
T Watamoto, H Egusa, T Sawase, H Yatani - Frontiers in Microbiology, 2015 - frontiersin.org
Candida species have emerged as important and common opportunistic human pathogens,
particularly in immunocompromised individuals. The current antifungal therapies either have …
particularly in immunocompromised individuals. The current antifungal therapies either have …
Susceptibility of Candida albicans biofilms to caspofungin and anidulafungin is not affected by metabolic activity or biomass production
Micafungin is more active against biofilms with high metabolic activity; however, it is
unknown whether this observation applies to caspofungin and anidulafungin and whether it …
unknown whether this observation applies to caspofungin and anidulafungin and whether it …
A novel small molecule inhibitor of Candida albicans biofilm formation, filamentation and virulence with low potential for the development of resistance
CG Pierce, AK Chaturvedi, AL Lazzell… - npj Biofilms and …, 2015 - nature.com
Methods: To address the pressing need for new antifungals, we have performed a high-
content screen of 20,000 small molecules in a chemical library (NOVACore) to identify …
content screen of 20,000 small molecules in a chemical library (NOVACore) to identify …
Cyclooxygenase inhibitors reduce biofilm formation and yeast-hypha conversion of fluconazole resistant Candida albicans
E Abdelmegeed, MI Shaaban - Journal of Microbiology, 2013 - Springer
The incidence of fluconazole-resistant Candida albicans has been increasing worldwide.
Both biofilm and fungal morphogenesis are main virulence factors of C. albicans cells …
Both biofilm and fungal morphogenesis are main virulence factors of C. albicans cells …
Candida virulence and ethanol‐derived acetaldehyde production in oral cancer and non‐cancer subjects
AD Alnuaimi, AN Ramdzan, D Wiesenfeld… - Oral …, 2016 - Wiley Online Library
Objectives To compare biofilm‐forming ability, hydrolytic enzymes and ethanol‐derived
acetaldehyde production of oral Candida isolated from the patients with oral cancer and …
acetaldehyde production of oral Candida isolated from the patients with oral cancer and …
[HTML][HTML] In vitro and in vivo effects of suloctidil on growth and biofilm formation of the opportunistic fungus Candida albicans
B Zeng, J Li, Y Wang, P Chen, X Wang, J Cui, L Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
As the most frequent fungal pathogen in humans, Candida albicans can develop serious
drug resistance because its biofilms are resistant to most antifungal agents; this leads to an …
drug resistance because its biofilms are resistant to most antifungal agents; this leads to an …
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