[PDF][PDF] Akkermansia muciniphila improves metabolic profiles by reducing inflammation in chow diet-fed mice

S Zhao, W Liu, J Wang, J Shi, Y Sun, W Wang… - J Mol …, 2017 - researchgate.net
Abnormal shifts in the composition of gut microbiota contribute to the pathogenesis of
metabolic diseases, including obesity and type 2 diabetes (T2DM). The crosstalk between …

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

A Everard, C Belzer, L Geurts… - Proceedings of the …, 2013 - National Acad Sciences
Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and
gut barrier disruption. Microbial composition and the mechanisms of interaction with the host …

Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice

M Schneeberger, A Everard, AG Gómez-Valadés… - Scientific reports, 2015 - nature.com
Recent evidence indicates that the gut microbiota plays a key role in the pathophysiology of
obesity. Indeed, diet-induced obesity (DIO) has been associated to substantial changes in …

Function of Akkermansia muciniphila in Obesity: Interactions With Lipid Metabolism, Immune Response and Gut Systems

Y Xu, N Wang, HY Tan, S Li, C Zhang… - Frontiers in …, 2020 - frontiersin.org
Obesity and its metabolic syndrome, including liver disorders and type 2 diabetes, are a
worldwide epidemic and are intimately linked to diet. The gut microbiota interaction has …

Comparative effects of alive and pasteurized Akkermansia muciniphila on normal diet-fed mice

F Ashrafian, S Keshavarz Azizi Raftar, A Shahryari… - Scientific reports, 2021 - nature.com
Recently, Akkermansia muciniphila an anaerobic member of the gut microbiota, has been
proposed as a next-generation probiotic. The aim of this study was evaluation of the effect of …

Polyphenols as Drivers of a Homeostatic Gut Microecology and Immuno-Metabolic Traits of Akkermansia muciniphila: From Mouse to Man

MC Rodríguez-Daza, WM de Vos - International Journal of Molecular …, 2022 - mdpi.com
Akkermansia muciniphila is a mucosal symbiont considered a gut microbial marker in
healthy individuals, as its relative abundance is significantly reduced in subjects with gut …

Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease in mice

HS Yoon, CH Cho, MS Yun, SJ Jang, HJ You… - Nature …, 2021 - nature.com
The gut microbiota, which includes Akkermansia muciniphila, is known to modulate energy
metabolism, glucose tolerance, immune system maturation and function in humans …

Akkermansia muciniphila and Gut Immune System: A Good Friendship That Attenuates Inflammatory Bowel Disease, Obesity, and Diabetes

VF Rodrigues, J Elias-Oliveira, ÍS Pereira… - Frontiers in …, 2022 - frontiersin.org
Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium
that colonizes the intestinal mucosa of humans and rodents. Metagenomic data have shown …

Akkermansia muciniphila-Derived Extracellular Vesicles as a Mucosal Delivery Vector for Amelioration of Obesity in Mice

F Ashrafian, A Shahriary, A Behrouzi… - Frontiers in …, 2019 - frontiersin.org
Recent evidence suggests that probiotics can restore the mucosal barrier integrity,
ameliorate inflammation, and promote homeostasis required for metabolism in obesity by …

Puerarin prevents high-fat diet-induced obesity by enriching Akkermansia muciniphila in the gut microbiota of mice

L Wang, Y Wu, L Zhuang, X Chen, H Min, S Song… - PLoS …, 2019 - journals.plos.org
Growing evidence indicates that the gut microbiota plays a significant role in the
pathophysiological processes of obesity and its related metabolic symptoms in the host …