Peripheral nerve injury (PNI) may lead to disability and neuropathic pain, which constitutes a
substantial economic burden to patients and society. It was found that the peripheral …

Abstract Non-coding RNAs (ncRNAs), especially microRNAs (miRNAs) and long non-coding
RNAs (lncRNAs), have attracted much attention since their regulatory roles in diverse cell …

Axons in the central nervous system often fail to regenerate after injury due to the limited
intrinsic regeneration ability of the central nervous system (CNS) and complex extracellular …

Non-coding RNAs (ncRNAs) are a large cluster of RNAs that do not encode proteins, but
have multiple functions in diverse cellular processes. Mounting evidence indicates the …

The intrinsic regeneration capacity of dorsal root ganglion (DRG) neurons can be activated
after sciatic nerve injury, and peripheral nerve regeneration is a complex process regulated …

Research has shown that long-chain noncoding RNAs (lncRNAs) are involved in the
regulation of a variety of biological processes, including peripheral nerve regeneration, in …

Peripheral nerve injury (PNI) is a common clinical problem, which can cause severe
disability and dramatically affect a patient's quality of life. Neural regeneration after PNI is a …

Schwann cells (SCs) contribute to nerve repair following injury; however, the underlying
molecular mechanism is poorly understood. MicroRNAs (miRNAs), which are short …

In mammals, long noncoding RNA (LncRNA) contributes to neuronal development and
injury repair mediated by the spatiotemporal regulation of gene expression. However, the …

As the major glia in PNS, Schwann cells play a critical role in peripheral nerve injury repair.
Finding an efficient approach to promote Schwann cell activation might facilitate peripheral …