High dietary sugar reshapes sweet taste to promote feeding behavior in Drosophila melanogaster
CE May, A Vaziri, YQ Lin, O Grushko, M Khabiri… - Cell reports, 2019 - cell.com
Recent studies find that sugar tastes less intense to humans with obesity, but whether this
sensory change is a cause or a consequence of obesity is unclear. To tackle this question …
sensory change is a cause or a consequence of obesity is unclear. To tackle this question …
Taste-independent detection of the caloric content of sugar in Drosophila
Feeding behavior is influenced primarily by two factors: nutritional needs and food
palatability. However, the role of food deprivation and metabolic needs in the selection of …
palatability. However, the role of food deprivation and metabolic needs in the selection of …
Integration of taste and calorie sensing in Drosophila
JW Stafford, KM Lynd, AY Jung… - Journal of …, 2012 - Soc Neuroscience
Animals use gustatory information to assess the suitability of potential food sources and
make critical decisions on what to consume. For example, the taste of sugar generally …
make critical decisions on what to consume. For example, the taste of sugar generally …
Physiological adaptations to sugar intake: new paradigms from Drosophila melanogaster
V Hietakangas, B Lemaitre - Trends in Endocrinology & Metabolism, 2017 - cell.com
Sugars are important energy sources, but high sugar intake poses a metabolic challenge
and leads to diseases. Drosophila melanogaster is a generalist fruit breeder that encounters …
and leads to diseases. Drosophila melanogaster is a generalist fruit breeder that encounters …
Secondary taste neurons that convey sweet taste and starvation in the Drosophila brain
P Kain, A Dahanukar - Neuron, 2015 - cell.com
The gustatory system provides vital sensory information to determine feeding and appetitive
learning behaviors. Very little is known, however, about higher-order gustatory circuits in the …
learning behaviors. Very little is known, however, about higher-order gustatory circuits in the …
Dietary macronutrient imbalances lead to compensatory changes in peripheral taste via independent signaling pathways
Food choice, in animals, has been known to change with internal nutritional state and also
with variable dietary conditions. To better characterize mechanisms of diet-induced plasticity …
with variable dietary conditions. To better characterize mechanisms of diet-induced plasticity …
Drosophila sugar receptors in sweet taste perception, olfaction, and internal nutrient sensing
Identification of nutritious compounds is dependent on expression of specific taste receptors
in appropriate taste-cell types [1]. In contrast to mammals, which rely on a single, broadly …
in appropriate taste-cell types [1]. In contrast to mammals, which rely on a single, broadly …
[HTML][HTML] Presynaptic gain control drives sweet and bitter taste integration in Drosophila
The sense of taste is critical in determining the nutritional suitability of foods. Sweet and
bitter are primary taste modalities in mammals, and their behavioral relevance is similar in …
bitter are primary taste modalities in mammals, and their behavioral relevance is similar in …
Pharyngeal sense organs drive robust sugar consumption in Drosophila
EE LeDue, YC Chen, AY Jung, A Dahanukar… - Nature …, 2015 - nature.com
The fly pharyngeal sense organs lie at the transition between external and internal nutrient-
sensing mechanisms. Here we investigate the function of pharyngeal sweet gustatory …
sensing mechanisms. Here we investigate the function of pharyngeal sweet gustatory …
Starvation-induced depotentiation of bitter taste in Drosophila
Nutrient deprivation can lead to dramatic changes in feeding behavior, including acceptance
of foods that are normally rejected. In flies, this behavioral shift depends in part on reciprocal …
of foods that are normally rejected. In flies, this behavioral shift depends in part on reciprocal …
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