Background Restless legs syndrome is a prevalent chronic neurological disorder with
potentially severe mental and physical health consequences. Clearer understanding of the …

Restless legs syndrome (RLS) is a common neurological sensorimotor disorder often
described as an unpleasant sensation associated with an urge to move the legs. Here we …

Restless legs syndrome (RLS) is a sensorimotor disorder with an age-dependent
prevalence of up to 10% in the general population above 65 years of age. Affected …

Restless legs syndrome (RLS) is a common neurological condition with three loci (12q, 14q,
and 9p) described so far, although none of these genes has yet been identified. We report a …

Restless legs syndrome (RLS) is a common neurological disorder that affects 5%–12% of all
whites. To genetically dissect this complex disease, we characterized 15 large and extended …

Recent publications on both the genetics and environmental factors of restless legs
syndrome (RLS) defined as a clinical disorder suggest that overlapping genetic risk factors …

Abstract Knowledge of restless legs syndrome (RLS) has greatly increased in recent years
due to the many advances that have been made in diagnosis, management and genetics …

Restless legs syndrome (RLS) is a highly familial trait with heritability estimates of about
50%. It is a polygenetic disorder in which a number of variants contribute to the phenotype …

Background: Restless legs syndrome (RLS) is associated with common variants in three
intronic and intergenic regions in MEIS1, BTBD9, and MAP2K5/LBXCOR1 on chromosomes …

Objectives To fully ascertain the familial aggregation of restless legs syndrome (RLS) and to
characterize the clinical features of familial RLS (fRLS) cases. Design A case series survey …