Tumor-associated macrophages (TAMs) promote metastasis and inhibit T cells, but
macrophages can be polarized to kill cancer cells. Macrophage polarization could thus be a …

Macrophages are phagocytes that serve as a first line of defense against pathogenic insults
to tissues. These innate immune cells mount proinflammatory responses to pathogens and …

Cancer immunotherapies that engage immune cells to fight against tumors are proving to be
powerful weapons in combating cancer and are becoming increasingly utilized in the clinics …

Simple Summary Tumor-associated macrophages (TAMs) coinhabit the tumor
microenvironment with cancer, immune, and stromal cells. They undermine the immune …

Cancer progression is primarily caused by interactions between transformed cells and the
components of the tumor microenvironment (TME). TAMs (tumor-associated macrophages) …

Smouldering inflammation is a component of the tumor microenvironment and represents
the 7th hallmark of cancer. Tumor-associated macrophages (TAM) have served as a …

Macrophages are important effector cells of the innate immune system and are also major
components of the tumor microenvironment (TME). Macrophages that are abundant in the …

Tumor-associated macrophages (TAMs), representing most of the leukocyte population in
solid tumors, demonstrate great phenotypic heterogeneity and diverse functional capabilities …

Tumor metastasis is a major contributor to the death of cancer patients. It is driven not only
by the intrinsic alterations in tumor cells, but also by the implicated cross-talk between …

The chronic inflammation of tumor continues to recruit TAMs (tumor− associated
macrophages) to the TME (tumor microenvironment) and promote polarization. Pro …