Diverse 2-pyridone alkaloids have been identified with an array of biological and
pharmaceutical activities, including the development of drugs. However, the biosynthetic …

Late stage oxidations during the biosynthesis of the 2-pyridone tenellin in the insect
pathogenic fungus Beauveria bassiana were investigated by a combination of gene …

Genomic DNA from the insect pathogenic fungus Beauveria bassiana was used as a
template in a PCR with degenerate primers designed to amplify a fragment of a C‐methyl …

Iron is an essential element for life. However, the iron overload can be toxic. Here, we
investigated the significant increase of tenellin and iron–tenellin complex production in …

Fungal reduced polyketides possess diverse structures exploring a broad region of chemical
space despite their synthesis by very similar enzymes. Many fungal polyketides are capped …

Fungi have the potential to produce a large repertoire of bioactive molecules, many of which
can affect the growth and development of plants. Genomic survey of sequenced biofertilizer …

Efficient iron acquisition mechanisms are fundamental for microbial survival in the
environment and for pathogen virulence within their hosts. M. robertsii produces two known …

Strategies are needed for the robust production of cryptic, silenced, or engineered
secondary metabolites in fungi. The filamentous fungus Fusarium heterosporum natively …

Metarhizium anisopliae is an important entomopathogenic species and model for arthropod-
fungus interaction studies. This fungus harbors a diverse arsenal of unexplored secondary …

Fungal polyketide synthases (PKSs) can function collaboratively to synthesize natural
products of significant structural diversity. Here we present a new mode of collaboration …