The biogenesis, biological functions, and applications of macrophage-derived exosomes

X Shan, C Zhang, C Mai, X Hu, N Cheng… - Frontiers in molecular …, 2021 - frontiersin.org
Macrophage-derived exosomes have been implicated on the modulation of inflammatory
processes. Recent studies have shown that macrophage-derived exosomes contribute to …

The novel target: exosoms derived from M2 macrophage

Y Hou, Y Liu, S Liang, R Ding, S Mo… - … Reviews of Immunology, 2021 - Taylor & Francis
More and more exosome-based therapeutics are being developed with advances in
nanotechnology and precision medicine. Exosome is a kind of tiny vesicles with a bilayer of …

Exosomes in inflammation and inflammatory disease

BD Chan, WY Wong, MML Lee, WCS Cho, BK Yee… - …, 2019 - Wiley Online Library
Exosomes are a subset of extracellular vesicles released by all cell types and involved in
local and systemic intercellular communication. In the past decade, research into exosomes …

Research progress in the application of exosomes in immunotherapy

X Zhang, D Xu, Y Song, R He, T Wang - Frontiers in Immunology, 2022 - frontiersin.org
Exosomes are nanoscale extracellular vesicles (EVs), which are present in all body fluids
tested. They are secreted by a variety of cells including macrophages, dendritic cells, mast …

The role of exosomes in inflammatory diseases and tumor-related inflammation

Y Tian, C Cheng, Y Wei, F Yang, G Li - Cells, 2022 - mdpi.com
Inflammation plays a decisive role in inducing tumorigenesis, promoting tumor development,
tumor invasion and migration. The interaction of cancer cells with their surrounding stromal …

A comprehensive review on factors influences biogenesis, functions, therapeutic and clinical implications of exosomes

S Gurunathan, MH Kang, JH Kim - International journal of …, 2021 - Taylor & Francis
Exosomes are nanoscale-sized membrane vesicles secreted by almost all cell types into the
extracellular environment upon fusion of multivesicular bodies and plasma membrane …

Macrophage-derived exosomes in cancers: Biogenesis, functions and therapeutic applications

J Liu, F Wu, H Zhou - Immunology Letters, 2020 - Elsevier
Macrophages are fundamental to promote tumorigenesis, tumor development and
metastasis, and chemotherapy resistance through modulating tumor microenvironment and …

Exosomes: new players in cell–cell communication

C Bang, T Thum - The international journal of biochemistry & cell biology, 2012 - Elsevier
Exosomes are small membrane vesicles of endosomal origin, which are secreted from a
variety of cell types. During the 1980s exosomes were first described as organelles to …

Macrophage-derived exosomes as advanced therapeutics for inflammation: current progress and future perspectives

Y Song, J Hu, C Ma, H Liu, Z Li… - International Journal of …, 2024 - Taylor & Francis
The development of numerous diseases is significantly influenced by inflammation.
Macrophage-derived exosomes (M-Exos) play a role in controlling inflammatory reactions in …

The multifaceted functions of exosomes in health and disease: an overview

C Arenaccio, M Federico - Exosomes in Cardiovascular Diseases …, 2017 - Springer
Exosomes are extracellular vesicles of 50–150 nm in diameter secreted by basically all cell
types. They mediate micro-communication among cells, tissues, and organs under both …